Transcriptional regulation of Wnt/β-catenin pathway in colorectal cancer
J Bian, M Dannappel, C Wan, R Firestein - Cells, 2020 - mdpi.com
The Wnt/β-catenin signaling pathway exerts integral roles in embryogenesis and adult
homeostasis. Aberrant activation of the pathway is implicated in growth-associated diseases …
homeostasis. Aberrant activation of the pathway is implicated in growth-associated diseases …
[HTML][HTML] The role of SOX family members in solid tumours and metastasis
Cancer is a heavy burden for humans across the world with high morbidity and mortality.
Transcription factors including sex determining region Y (SRY)-related high-mobility group …
Transcription factors including sex determining region Y (SRY)-related high-mobility group …
[HTML][HTML] Upregulated lncRNA SNHG1 contributes to progression of non-small cell lung cancer through inhibition of miR-101-3p and activation of Wnt/β-catenin …
Y Cui, F Zhang, C Zhu, L Geng, T Tian, H Liu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Lung cancer is the most common and aggressive tumor in the world. Long non-coding RNA
small nucleolar RNA host gene 1 (lncRNA SNHG1) play critical roles in the progression of …
small nucleolar RNA host gene 1 (lncRNA SNHG1) play critical roles in the progression of …
Deep top-down proteomics revealed significant proteoform-level differences between metastatic and nonmetastatic colorectal cancer cells
Understanding cancer metastasis at the proteoform level is crucial for discovering previously
unknown protein biomarkers for cancer diagnosis and drug development. We present the …
unknown protein biomarkers for cancer diagnosis and drug development. We present the …
High recovery FASP applied to the proteomic analysis of microdissected formalin fixed paraffin embedded cancer tissues retrieves known colon cancer markers
JR Wisniewski, P Ostasiewicz… - Journal of proteome …, 2011 - ACS Publications
Proteomic analysis of samples isolated by laser capture microdissection from clinical
specimens requires sample preparation and fractionation methods suitable for small …
specimens requires sample preparation and fractionation methods suitable for small …
Oncogenicity of the developmental transcription factor Sox9
A Matheu, M Collado, C Wise, L Manterola, L Cekaite… - Cancer research, 2012 - AACR
SOX9 [sex-determining region Y (SRY)-box 9 protein], a high mobility group box
transcription factor, plays critical roles during embryogenesis and its activity is required for …
transcription factor, plays critical roles during embryogenesis and its activity is required for …
SOX9 drives WNT pathway activation in prostate cancer
The transcription factor SOX9 is critical for prostate development, and dysregulation of SOX9
is implicated in prostate cancer (PCa). However, the SOX9-dependent genes and pathways …
is implicated in prostate cancer (PCa). However, the SOX9-dependent genes and pathways …
SOX9: An emerging driving factor from cancer progression to drug resistance
Dysregulation of transcription factors is one of the common problems in the pathogenesis of
human cancer. Among them, SOX9 is one of the critical transcription factors involved in …
human cancer. Among them, SOX9 is one of the critical transcription factors involved in …
SOX9 drives the epithelial–mesenchymal transition in non-small-cell lung cancer through the Wnt/β-catenin pathway
JQ Huang, FK Wei, XL Xu, SX Ye, JW Song… - Journal of translational …, 2019 - Springer
Background The distant metastasis of cancer cells is a risk factor for tumor lethality and poor
prognosis in non-small-cell lung carcinoma (NSCLC). Increased SOX9 expression has been …
prognosis in non-small-cell lung carcinoma (NSCLC). Increased SOX9 expression has been …
[HTML][HTML] Tumor-associated macrophages promote tumor metastasis via the TGF-β/SOX9 axis in non-small cell lung cancer
Abstract Tumor-associated macrophages (TAMs), most of which display the
immunosuppressive M2 phenotype, affect the tumor microenvironment and promote …
immunosuppressive M2 phenotype, affect the tumor microenvironment and promote …