A new edition of the WHO classification of tumours of the CNS was published in 2021.
Although the previous edition of this classification was published just 5 years earlier, in …

Simple Summary Medulloblastoma is the most common pediatric brain tumor, comprising
one-third of all pediatric brain tumors, and originating in the posterior fossa of the brain. The …

Critical discoveries over the past two decades have transformed our understanding of
medulloblastoma from a single entity into a clinically and biologically heterogeneous …

Simple Summary Brain tumors remain the most common childhood solid tumors, accounting
for approximately 25% of all pediatric cancers. They also represent the most common cause …

Simple Summary The European trial SIOP PNET5 MB was initiated in 2014 and will remain
open to recruitment until 2022. It is the first European trial using clinical, histological, and …

Abstract Purpose of Review Review recent advances in the understanding of pediatric
medulloblastoma including etiology, biology, radiology, and management of pediatric …

Medulloblastoma (MB) is the most common malignant central nervous system tumor in
pediatric patients. Mainstay of therapy remains surgical resection followed by craniospinal …

Tumors of CNS are common in adolescents and young adults (AYAs). As the second
leading cause of cancer-related death, CNS tumors in AYAs require improved clinical …

Medulloblastoma is the most common malignant brain tumor in children. Over the last few
decades, significant progress has been made in revealing the key molecular underpinnings …

While in adults most intracranial tumors develop around the cerebral hemispheres, 45 to
60% of pediatric lesions are found in the posterior fossa, although this anatomical region …