DNA is continuously attacked by reactive species that can affect its structure and function
severely. Structural modifications to DNA mainly arise from modifications in its bases that …

Cancer is irrevocably linked to aberrant metabolic processes. While once considered a
vestigial organelle, we now know that peroxisomes play a central role in the metabolism of …

Chemical modifications of DNA and RNA regulate genome functions or trigger mutagenesis
resulting in aging or cancer. Oxidations of macromolecules, including DNA, are common …

The reaction of hydroxyl radical (OH•) with DNA accounts for about half of radiation-induced
DNA damage in living systems. Previous literature reports point out that the reaction of OH• …

DNA damage by endogenous and exogenous agents is a serious concern, as the damaged
products can affect genome integrity severely. Damage to DNA may arise from various …

Cold atmospheric pressure plasmas have proven to provide an alternative treatment of
cancer by targeting tumorous cells while leaving their healthy counterparts unharmed …

The potential energy surface for formation of 2-amino-5-hydroxy-7, 9-dihydropurine-6, 8-
dione (5-OH-OG), guanidinohydantoin (Gh) and spiroiminodihydantoin (Sp) from 8 …

Alterations of DNA repair enzymes and consequential triggering of aberrant DNA damage
response (DDR) pathways are thought to play a pivotal role in genomic instabilities …

Curcumin is known to be an antioxidant, as it can scavenge free radicals from biological
media. A sequence of H-abstraction and addition reactions involving up to eight OH radicals …

Modelling at the molecular or atomic scale can be very useful for obtaining a better insight in
plasma medicine. This paper gives an overview of different atomic/molecular scale …