Metals in Alzheimer's disease

M Babić Leko, L Langer Horvat, E Španić Popovački… - Biomedicines, 2023 - mdpi.com
The role of metals in the pathogenesis of Alzheimer's disease (AD) is still debated. Although
previous research has linked changes in essential metal homeostasis and exposure to …

Aluminium in cosmetics and personal care products

S Sanajou, G Şahin, T Baydar - Journal of Applied Toxicology, 2021 - Wiley Online Library
Usage of inorganic ingredients like aluminium salts in cosmetics and personal care products
has been a concern for producers and consumers. Although aluminium is used to treat …

Dauricine alleviates cognitive impairment in Alzheimer's disease mice induced by D-galactose and AlCl3 via the Ca2+/CaM pathway

JS Xue, JQ Li, CC Wang, XH Ma, H Dai, CB Xu… - Toxicology and Applied …, 2023 - Elsevier
Alzheimer's disease (AD) is a common neurodegenerative disease in the elderly.
Dysregulation of intracellular Ca 2+ homeostasis plays a critical role in the pathological …

Role of aluminum exposure on Alzheimer's disease and related glycogen synthase kinase pathway

S Sanajou, P Erkekoğlu, G Şahin… - Drug and chemical …, 2023 - Taylor & Francis
Aluminum (Al) is an environmentally abundant metal that is not essential for life. There is
considerable evidence that Al as a neurotoxic xenobiotic may play a role in the …

Neuroprotective Effect of Thiazolidine-2, 4-dione Derivatives on Memory Deficits and Neuropathological Symptoms of Dementia on a Scopolamine-Induced …

M Taheri, H Ghafoori, H Sepehri… - ACS Chemical …, 2023 - ACS Publications
Alzheimer's disease (AD) is a neurodegenerative disorder associated with a decline in
memory deficits and neuropathological diagnosis with loss of cholinergic neurons in the …

Neuron protection by EDTA may explain the successful outcomes of toxic metal chelation therapy in neurodegenerative diseases

ME Ferrero - Biomedicines, 2022 - mdpi.com
Many mechanisms have been related to the etiopathogenesis of neurodegenerative
diseases (NDs) such as multiple sclerosis, amyotrophic lateral sclerosis, Parkinson's …

Air pollution: a silent key driver of dementia

P Serafin, M Zaremba, D Sulejczak, P Kleczkowska - Biomedicines, 2023 - mdpi.com
In 2017, the Lancet Commission on Dementia Prevention, Intervention, and Care included
air pollution in its list of potential risk factors for dementia; in 2018, the Lancet Commission …

Tubulin Cytoskeleton in Neurodegenerative Diseases–not Only Primary Tubulinopathies

Z Cyske, L Gaffke, K Pierzynowska… - Cellular and Molecular …, 2023 - Springer
Neurodegenerative diseases represent a large group of disorders characterized by gradual
loss of neurons and functions of the central nervous systems. Their course is usually severe …

Trace elements released from dental implants with periimplantitis: A cohort study

G Gürbüz-Urvasızoğlu, M Ataol, FB Özgeriş - Irish Journal of Medical …, 2022 - Springer
Abstract Background Pure titanium and Ti6Al4V alloy have been in use as dental implant
contemporarily. Trace element release from implant bodies is a possible health problem …

Spermine protects aluminium chloride and iron-induced neurotoxicity in rat model of Alzheimer's disease via attenuation of tau phosphorylation, Amyloid-β (1–42) and …

K Raj, GD Gupta, S Singh - Inflammopharmacology, 2021 - Springer
Alzheimer's disease (AD) is the most prevalent type of dementia, characterized by a gradual
decline in cognitive and memory functions of the aged peoples. Long-term exposure to …