Autism spectrum disorder: neurodevelopmental risk factors, biological mechanism, and precision therapy
L Wang, B Wang, C Wu, J Wang, M Sun - International journal of …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a heterogeneous, behaviorally defined
neurodevelopmental disorder. Over the past two decades, the prevalence of autism …
neurodevelopmental disorder. Over the past two decades, the prevalence of autism …
Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders
LG Costa, TB Cole, K Dao, YC Chang, J Coburn… - Pharmacology & …, 2020 - Elsevier
Recent extensive evidence indicates that air pollution, in addition to causing respiratory and
cardiovascular diseases, may also negatively affect the brain and contribute to central …
cardiovascular diseases, may also negatively affect the brain and contribute to central …
Synaptopathology involved in autism spectrum disorder
Autism spectrum disorder (ASD) encompasses a group of multifactorial neurodevelopmental
disorders characterized by impaired social communication, social interaction and repetitive …
disorders characterized by impaired social communication, social interaction and repetitive …
Elevated levels of FMRP-target MAP1B impair human and mouse neuronal development and mouse social behaviors via autophagy pathway
Fragile X messenger ribonucleoprotein 1 protein (FMRP) binds many mRNA targets in the
brain. The contribution of these targets to fragile X syndrome (FXS) and related autism …
brain. The contribution of these targets to fragile X syndrome (FXS) and related autism …
The SLC9A-C mammalian Na+/H+ exchanger family: molecules, mechanisms, and physiology
SF Pedersen, L Counillon - Physiological reviews, 2019 - journals.physiology.org
Na+/H+ exchangers play pivotal roles in the control of cell and tissue pH by mediating the
electroneutral exchange of Na+ and H+ across cellular membranes. They belong to an …
electroneutral exchange of Na+ and H+ across cellular membranes. They belong to an …
Targeting PI3K-AKT/mTOR signaling in the prevention of autism
A Sharma, S Mehan - Neurochemistry international, 2021 - Elsevier
Abstract PI3K-AKT/mTOR signaling pathway represents an essential signaling mechanism
for mammalian enzyme-related receptors in transducing signals or biological processes …
for mammalian enzyme-related receptors in transducing signals or biological processes …
RNA-binding proteins balance brain function in health and disease
R Schieweck, J Ninkovic… - Physiological reviews, 2021 - journals.physiology.org
Posttranscriptional gene expression including splicing, RNA transport, translation, and RNA
decay provides an important regulatory layer in many if not all molecular pathways …
decay provides an important regulatory layer in many if not all molecular pathways …
Brain-based sex differences in autism spectrum disorder across the lifespan: A systematic review of structural MRI, fMRI, and DTI findings
Females with autism spectrum disorder (ASD) have been long overlooked in neuroscience
research, but emerging evidence suggests they show distinct phenotypic trajectories and …
research, but emerging evidence suggests they show distinct phenotypic trajectories and …
Propionic acid induces gliosis and neuro-inflammation through modulation of PTEN/AKT pathway in autism spectrum disorder
LS Abdelli, A Samsam, SA Naser - Scientific reports, 2019 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by glia
over-proliferation, neuro-inflammation, perturbed neural circuitry, and gastrointestinal …
over-proliferation, neuro-inflammation, perturbed neural circuitry, and gastrointestinal …
Assessment of behavioral, morphological and electrophysiological changes in prenatal and postnatal valproate induced rat models of autism spectrum disorder
K Fereshetyan, V Chavushyan, M Danielyan… - Scientific reports, 2021 - nature.com
Autism spectrum disorders (ASD) are neurodevelopmental disorders, that are characterized
by core symptoms, such as alterations of social communication and restrictive or repetitive …
by core symptoms, such as alterations of social communication and restrictive or repetitive …