Modulation of neurotransmission by purine nucleotides and nucleosides

BB Fredholm, P Hedqvist - Biochemical pharmacology, 1980 - Elsevier
This commentary will briefly summarize the growing body of evidence suggesting that
extracellular purine compounds, by acting at a postulated cell membrane receptor, cause a …

The role of purines in nociception

J Sawynok, MI Sweeney - Neuroscience, 1989 - Elsevier
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Adenosine decreases aspartate and glutamate release from rat hippocampal slices

R Corradetti, GL Conte, F Moroni, MB Passani… - European journal of …, 1984 - Elsevier
The effect of adenosine and related compounds on the release of endogenous aspartate
and glutamate from isolated, superfused rat hippocampal slices was studied at rest and …

Purine levels in the intact rat brain. Studies with an implanted perfused hollow fibre

T Zetterström, L Vernet, U Ungerstedt, U Tossman… - Neuroscience …, 1982 - Elsevier
A thin dialysis tube was implanted stereotaxically under halothane anesthesia in the
caudate nucleus of Sprague-Dawley rats and perfused with Ringer solution at a rate of 2 …

Alkylxanthines elevate hippocampal excitability: evidence for a role of endogenous adenosine

TV Dunwiddie, BJ Hoffer, BB Fredholm - Naunyn-Schmiedeberg's archives …, 1981 - Springer
The effects of four xanthines (theophylline, 8-phenyltheophylline, isobutylmethylxanthine
(IBMX), and 7-benzyl-IBMX) were studied in the hippocampal slice in vitro. These agents …

Hereditary covariations of neuronal circuitry and behavior: correlations between the proportions of hippocampal synaptic fields in the regio inferior and two-way …

H Schwegler, HP Lipp - Behavioural brain research, 1983 - Elsevier
By means of Timm's silver sulfide stain, the proportions of synaptic terminal fields covering
cross-sections from the regio inferior of the hippocampus were determined planimetrically at …

An A1-adenosine receptor, characterized by [3H] cyclohexyladenosine binding, mediates the depression of evoked potentials in a rat hippocampal slice preparation

M Reddington, KS Lee, P Schubert - Neuroscience letters, 1982 - Elsevier
In slices of rat hippocampus, adenosine and several adenosine derivatives depressed
evoked neuronal responses to afferent stimulation. The nanomolar potency of adenosine …

Adenosine depression of hippocampal neurons in vitro: an intracellular study of dose-dependent actions on synaptic and membrane potentials

GR Siggins, P Schubert - Neuroscience letters, 1981 - Elsevier
In CA1 pyramidal neurons, 5 μM adenosine had no measurable effect on resting membrane
potential or resistance, while excitatory and inhibitory postsynaptic potentials generated by …

Melanin: the organizing molecule

FE Barr, JS Saloma, MJ Buchele - Medical Hypotheses, 1983 - Elsevier
The hypothesis is advanced that (neuro) melanin (in conjunction with other pigment
molecules such as the isopentenoids) functions as the major organizational molecule in …

Electrophysiology of benzodiazepine receptor ligands: multiple mechanisms and sites of action

P Polc - Progress in neurobiology, 1988 - Elsevier
Electrophysiology of BZR ligands has been reviewed from different points of view. A great
effort was made to critically discuss the arguments for and against the temporarily leading …