Although magnesium is involved in a wide spectrum of vital functions in normal human
physiology, the significance of hypomagnesemia and necessity for its treatment are under …

K+ channels fulfill roles spanning from the control of excitability to the regulation of
transepithelial transport. Here we review two groups of K+ channels, pH-regulated K2P …

Kir4. 1 in the distal convoluted tubule plays a key role in sensing plasma potassium and in
modulating the thiazide-sensitive sodium-chloride cotransporter (NCC). Here we tested …

Supplementing diets with high potassium helps reduce hypertension in humans. Inwardly
rectifying K+ channels K ir 4.1 (Kcnj10) and K ir 5.1 (Kcnj16) are highly expressed in the …

More than two dozen types of potassium channels, with different biophysical and regulatory
properties, are expressed in the kidney, influencing renal function in many important ways …

The aim of this mini review is to provide an overview regarding the role of inwardly rectifying
potassium channel 4.1 (Kir4. 1)/Kir5. 1 in regulating renal K+ excretion. Deletion of Kir4. 1 in …

The inwardly rectifying potassium channel (Kir) 4.1 (encoded by KCNJ10) interacts with Kir5.
1 (encoded by KCNJ16) to form a major basolateral K+ channel in the renal distal …

Inward rectifying potassium (Kir) channels play important roles in both excitable and
nonexcitable cells of various organ systems and could represent valuable new drug targets …

Initial clearance of extracellular K+([K+] o) following neuronal excitation occurs by astrocytic
uptake, because elevated [K+] o activates astrocytic but not neuronal Na+, K+-ATPases …

The inward rectifier potassium (Kir) channel Kir4. 1 (KCNJ10) carries out important
physiologic roles in epithelial cells of the kidney, astrocytes in the central nervous system …