Polymerase chain reaction in microfluidic devices
The invention of the polymerase chain reaction (PCR) has caused a revolution in molecular
biology, giving access to a method of amplifying deoxyribonucleic acid (DNA) molecules …
biology, giving access to a method of amplifying deoxyribonucleic acid (DNA) molecules …
Microfluidic DNA amplification—A review
Y Zhang, P Ozdemir - Analytica chimica acta, 2009 - Elsevier
The application of microfluidic devices for DNA amplification has recently been extensively
studied. Here, we review the important development of microfluidic polymerase chain …
studied. Here, we review the important development of microfluidic polymerase chain …
Micro total analysis systems: latest achievements
The field of micro total analysis systems (μTAS), or “lab on a chip”, has continued to gain
maturity. The importance of μTAS is reflected in both the growing number and the improved …
maturity. The importance of μTAS is reflected in both the growing number and the improved …
Multiplexed real-time polymerase chain reaction on a digital microfluidic platform
Z Hua, JL Rouse, AE Eckhardt, V Srinivasan… - Analytical …, 2010 - ACS Publications
This paper details the development of a digital microfluidic platform for multiplexed real-time
polymerase chain reactions (PCR). Liquid samples in discrete droplet format are …
polymerase chain reactions (PCR). Liquid samples in discrete droplet format are …
Simplifying the complex: accessible microfluidic solutions for contemporary processes within in vitro diagnostics
In vitro diagnostics (IVDs) form the cornerstone of modern medicine. They are routinely
employed throughout the entire treatment pathway, from initial diagnosis through to …
employed throughout the entire treatment pathway, from initial diagnosis through to …
Single-molecule DNA amplification and analysis using microfluidics
C Zhang, D Xing - Chemical reviews, 2010 - ACS Publications
The broad availability of amplified DNA molecules enabled the development of many
powerful applications in molecular biology techniques. Currently, a variety of DNA …
powerful applications in molecular biology techniques. Currently, a variety of DNA …
Microfluidic-based nucleic acid amplification systems in microbiology
Rapid, sensitive, and selective bacterial detection is a hot topic, because the progress in this
research area has had a broad range of applications. Novel and innovative strategies for …
research area has had a broad range of applications. Novel and innovative strategies for …
High-throughput real-time electrochemical monitoring of LAMP for pathogenic bacteria detection
One of the significant challenges in healthcare is the development of point-of-care (POC)
diagnostics. POC diagnostics require low-cost devices that offer portability, simplicity in …
diagnostics. POC diagnostics require low-cost devices that offer portability, simplicity in …
Microfluidic chip: next-generation platform for systems biology
X Feng, W Du, Q Luo, BF Liu - Analytica Chimica Acta, 2009 - Elsevier
Systems biology advocates the understanding of biology at the systems-level, which
requires massive information of correlations among individual components in complex …
requires massive information of correlations among individual components in complex …
The development of a portable buoyancy-driven PCR system and its evaluation by capillary electrophoresis
Rapid, low cost, and portable polymerase chain reaction system (PCR) can advance the
diagnosis of infectious disease, especially for the third-world countries. Herein, we …
diagnosis of infectious disease, especially for the third-world countries. Herein, we …