Histone deacetylases (HADC) are the enzymes that remove acetyl group from lysine residue
of histones and non-histone proteins and regulate the process of transcription by binding to …

Spinal cord injury (SCI) is one of the most debilitating of all the traumatic conditions that
afflict individuals. For a number of years, extensive studies have been conducted to clarify …

Cervical spondylotic myelopathy (CSM) is a common disorder involving chronic progressive
compression of the cervical spinal cord due to degenerative disc disease, spondylosis, or …

The inability of axons to regenerate after a spinal cord injury in the adult mammalian central
nervous system (CNS) can lead to permanent paralysis. At sites of CNS injury, a glial scar …

Once their safety is confirmed, human-induced pluripotent stem cells (hiPSCs), which do not
entail ethical concerns, may become a preferred cell source for regenerative medicine …

Surgical repair of severe peripheral nerve injuries represents not only a pressing medical
need, but also a great clinical challenge. Autologous nerve grafting remains a golden …

Central pattern generators are neuronal circuits that when activated can produce rhythmic
motor patterns such as walking, breathing, flying, and swimming in the absence of sensory …

▪ Abstract Nerve regeneration is a complex biological phenomenon. In the peripheral
nervous system, nerves can regenerate on their own if injuries are small. Larger injuries …

Stem cell therapies are being explored extensively as treatments for degenerative eye
disease, either for replacing lost neurons, restoring neural circuits or, based on more recent …

A specific genetic factor that strongly influences human physical performance has not so far
been reported, but here we show that a polymorphism in the gene encoding angiotensin …