Myelinated nerve fibers have evolved to enable fast and efficient transduction of electrical
signals in the nervous system. To act as an electric insulator, the myelin sheath is formed as …

Myelination of axons in the nervous system of vertebrates enables fast, saltatory impulse
propagation, one of the best-understood concepts in neurophysiology. However, it took a …

Human brain imaging has identified structural changes in gray and white matter that occur
with learning. However, ascribing imaging measures to underlying cellular and molecular …

Neuregulins (NRGs) comprise a large family of growth factors that stimulate ERBB receptor
tyrosine kinases. NRGs and their receptors, ERBBs, have been identified as susceptibility …

The myelination of axons by glial cells was the last major step in the evolution of cells in the
vertebrate nervous system, and white-matter tracts are key to the architecture of the …

Myelin is a defining feature of the vertebrate nervous system. Variability in the thickness of
the myelin envelope is a structural feature affecting the conduction of neuronal signals …

Intraventricular haemorrhage (IVH) continues to be a major complication of prematurity that
can result in cerebral palsy and cognitive impairment in survivors. No optimal therapy exists …

Progressive phases of multiple sclerosis are associated with inhibited differentiation of the
progenitor cell population that generates the mature oligodendrocytes required for …

Pro-regenerative macrophages are well known for their role in promoting tissue repair;
however, their specific roles in promoting regeneration of the injured nerve are not well …

During the menopausal transition, which begins four to six years before cessation of
menses, middle-aged women experience a progressive change in ovarian activity and a …