SLiM 4: multispecies eco-evolutionary modeling
The SLiM software framework for genetically explicit forward simulation has been widely
used in population genetics. However, it has been largely restricted to modeling only a …
used in population genetics. However, it has been largely restricted to modeling only a …
The immediate costs and long‐term benefits of assisted gene flow in large populations
With the genetic health of many plant and animal populations deteriorating due to climate
change outpacing adaptation, interventions, such as assisted gene flow (AGF), may provide …
change outpacing adaptation, interventions, such as assisted gene flow (AGF), may provide …
Using computational simulations to model deleterious variation and genetic load in natural populations
CC Kyriazis, JA Robinson… - The American …, 2023 - journals.uchicago.edu
Deleterious genetic variation is abundant in wild populations, and understanding the
ecological and conservation implications of such variation is an area of active research …
ecological and conservation implications of such variation is an area of active research …
Using computational simulations to quantify genetic load and predict extinction risk
Small and isolated wildlife populations face numerous threats to extinction, among which is
the deterioration of fitness due to an accumulation of deleterious genetic variation. Genomic …
the deterioration of fitness due to an accumulation of deleterious genetic variation. Genomic …
Dominance can increase genetic variance after a population bottleneck: A synthesis of the theoretical and empirical evidence
Drastic reductions in population size, or population bottlenecks, can lead to a reduction in
additive genetic variance and adaptive potential. Genetic variance for some quantitative …
additive genetic variance and adaptive potential. Genetic variance for some quantitative …
The genetics of assisted gene flow: immediate costs and long-term benefits
JA Grummer, TR Booker, R Matthey-Doret… - BioRxiv, 2021 - biorxiv.org
Plant and animal populations are facing several novel risks such as human-mediated
habitat fragmentation and climate change that threaten their long-term productivity and …
habitat fragmentation and climate change that threaten their long-term productivity and …
GSpace: an exact coalescence simulator of recombining genomes under isolation by distance
Motivation Simulation-based inference can bypass the limitations of statistical methods
based on analytical approximations, but software allowing simulation of structured …
based on analytical approximations, but software allowing simulation of structured …
[图书][B] Understanding the impact of deleterious genetic variation on extinction risk in small populations
CC Kyriazis - 2022 - search.proquest.com
Deleterious genetic variation is abundant in wild populations and can contribute to extinction
when populations become small and isolated. For example, elevated levels of inbreeding in …
when populations become small and isolated. For example, elevated levels of inbreeding in …
Coalescent tree recording with selection for fast forward-in-time simulations
R Matthey-Doret - bioRxiv, 2021 - biorxiv.org
Forward simulations are increasingly important in evolutionary genetics to simulate selection
with realistic demography, mating systems and ecology. To reach the performance needed …
with realistic demography, mating systems and ecology. To reach the performance needed …