Emerging Alzheimer's disease therapeutics: promising insights from lipid metabolism and microglia-focused interventions
NS Tobeh, KD Bruce - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
More than 55 million people suffer from dementia, with this number projected to double
every 20 years. In the United States, 1 in 3 aged individuals dies from Alzheimer's disease …
every 20 years. In the United States, 1 in 3 aged individuals dies from Alzheimer's disease …
Lipoprotein Particles in Cerebrospinal Fluid
M Tsujita, JT Melchior, S Yokoyama - … , Thrombosis, and Vascular …, 2024 - Am Heart Assoc
The brain is the most lipid-rich organ in the body, and the intricate interplay between lipid
metabolism and pathologies associated with neurodegenerative disorders is being …
metabolism and pathologies associated with neurodegenerative disorders is being …
Endosomal escape of RNA therapeutics
H Du Rietz - 2024 - portal.research.lu.se
RNA therapeutics is a new class of targeted therapies that has entered the clinic in the last
decade. Lipid nanoparticles (LNPs) and conjugation to N-acetylgalactosamine have proven …
decade. Lipid nanoparticles (LNPs) and conjugation to N-acetylgalactosamine have proven …