Neurobiological mechanisms of the onset of puberty in primates

EI Terasawa, DL Fernandez - Endocrine reviews, 2001 - academic.oup.com
An increase in pulsatile release of LHRH is essential for the onset of puberty. However, the
mechanism controlling the pubertal increase in LHRH release is still unclear. In primates the …

Hypothalamic tanycytes: a key component of brain–endocrine interaction

EM Rodríguez, JL Blázquez, FE Pastor… - International review of …, 2005 - Elsevier
Tanycytes are bipolar cells bridging the cerebrospinal fluid (CSF) to the portal capillaries
and may link the CSF to neuroendocrine events. During the perinatal period a …

Identification and characterization of a gonadotropin-inhibitory system in the brains of mammals

LJ Kriegsfeld, DF Mei, GE Bentley… - Proceedings of the …, 2006 - National Acad Sciences
Successful reproduction requires maintenance of the reproductive axis within fine operating
limits through negative feedback actions of sex steroids. Despite the importance of this …

Multimodal influence of estrogen upon gonadotropin-releasing hormone neurons

AE Herbison - Endocrine reviews, 1998 - academic.oup.com
Multimodal Influence of Estrogen upon Gonadotropin-Releasing Hormone Neurons | Endocrine
Reviews | Oxford Academic Skip to Main Content Advertisement Oxford Academic Journals …

The neuroendocrine timing of puberty

FJP Ebling - Reproduction, 2005 - rep.bioscientifica.com
Puberty is the attainment of fertility, a process encompassing morphological, physiological
and behavioural development. The increased hypothalamic secretion of the gonadotrophin …

Neuroendocrine regulation of GnRH release in induced ovulators

J Bakker, MJ Baum - Frontiers in neuroendocrinology, 2000 - Elsevier
GnRH is the key neuropeptide controlling reproductive function in all vertebrate species.
Two different neuroendocrine mechanisms have evolved among female mammals to …

Gonadotropin-releasing hormone genes: phylogeny, structure, and functions

RD Fernald, RB White - Frontiers in neuroendocrinology, 1999 - Elsevier
Gonadotropin-releasing hormone (GnRH, previously called leutinizing hormone-releasing
hormone, LHRH) is the final common signaling molecule used by the brain to regulate …

IGF-1 in the brain as a regulator of reproductive neuroendocrine function

SS Daftary, AC Gore - Experimental biology and medicine, 2005 - journals.sagepub.com
Given the close relationship among neuroendocrine systems, it Is likely that there may be
common signals that coordinate the acquisition of adult reproductive function with other …

IGSF10 mutations dysregulate gonadotropin‐releasing hormone neuronal migration resulting in delayed puberty

SR Howard, L Guasti, G Ruiz‐Babot… - EMBO molecular …, 2016 - embopress.org
Early or late pubertal onset affects up to 5% of adolescents and is associated with adverse
health and psychosocial outcomes. Self‐limited delayed puberty (DP) segregates …

[图书][B] GnRH: the master molecule of reproduction

AC Gore - 2002 - books.google.com
Gonadotropin-releasing hormone (GnRH) cells are the key regulators of reproductive
function in all vertebrate organisms. The GnRH molecule is synthesized in a small number of …