This article discusses the potential of Zebrafish (ZF)(Danio Rerio), as a model for epilepsy
research. Epilepsy is a neurological disorder affecting both children and adults, and many …

Rare genetic diseases are a group of pathologies with often unmet clinical needs. Even if
rare by a single genetic disease (from 1/2000 to 1/more than 1,000,000), the total number of …

The use of zebrafish as a model organism is gaining evidence in the field of epilepsy as it
may help to understand the mechanisms underlying epileptic seizures. As zebrafish assays …

In the past decades, zebrafish have gathered immense attention and importance in the field
of neurological sciences. In the case of epilepsy, zebrafish have appeared as a promising …

Background Epilepsy is a prevalent neurological disease, affecting approximately 1–2% of
the global population. The hallmark of epilepsy is the occurrence of epileptic seizures, which …

While the developmental neurotoxicity of perfluorooctane sulfonate (PFOS) has been
reported, its seizurogenic potential has not been investigated. Behavior assessment was …

Zebrafish (Danio rerio) assays provide a versatile pharmacological platform to test
compounds on a wide range of behaviors in a whole organism. A major challenge lies in the …

Abstract Sudden Unexpected Death in Epilepsy (SUDEP) is primarily linked with the cardiac
irregularities that occur due to recurrent seizures. Our previous studies found a role of mTOR …

A high-fat diet with appropriate protein and low carbohydrate content, widely known as the
ketogenic diet (KD), is considered as an effective non-pharmacotherapeutic treatment option …

α-Lipoic acid (LA), a dithiol micronutrient, acts as a vital cofactor in various cellular catabolic
reactions and is also known as a universal antioxidant. The therapeutic efficacy of LA is …