Recent progress in biosensor regeneration techniques

Y Jia, S Chen, Q Wang, J Li - Nanoscale, 2024 - pubs.rsc.org
Biosensors are widely used in various applications, from medical diagnostics to
environmental monitoring. Their widespread and continuous use necessitates regeneration …

Folding Double‐Stranded DNA into Designed Shapes with Triplex‐Forming Oligonucleotides

C Ng, A Samanta, OA Mandrup, E Tsang… - Advanced …, 2023 - Wiley Online Library
The compaction and organization of genomic DNA is a central mechanism in eukaryotic
cells, but engineered architectural control over double‐stranded DNA (dsDNA) is notably …

DNMG: Deep molecular generative model by fusion of 3D information for de novo drug design

T Song, Y Ren, S Wang, P Han, L Wang, X Li… - Methods, 2023 - Elsevier
Deep learning is improving and changing the process of de novo molecular design at a
rapid pace. In recent years, great progress has been made in drug discovery and …

DUHI: dynamically updated hash index clustering method for DNA storage

P Wang, B Cao, T Ma, B Wang, Q Zhang… - Computers in Biology and …, 2023 - Elsevier
The exponential growth of global data leads to the problem of insufficient data storage
capacity. DNA storage can be an ideal storage method due to its high storage density and …

TTSBBC: triplex target site biomarkers and barcodes in cancer

M Ylagan, Q Xu, J Kowalski - Nucleic Acids Research, 2024 - academic.oup.com
The technology of triplex-forming oligonucleotides (TFOs) provides an approach to
manipulate genes at the DNA level. TFOs bind to specific sites on genomic DNA, creating a …

Reconfigurable DNA triplex structure for pH responsive logic gates

M Qi, P Shi, X Zhang, S Cui, Y Liu, S Zhou, Q Zhang - RSC advances, 2023 - pubs.rsc.org
The DNA triplex is a special DNA structure often used as a logic gate substrate due to its
high stability, programmability, and pH responsiveness. However, multiple triplex structures …

A DNA Finite-State Machine Based on the Programmable Allosteric Strategy of DNAzyme

J Wang, X Zhang, P Shi, B Cao, B Wang - International Journal of …, 2023 - mdpi.com
Living organisms can produce corresponding functions by responding to external and
internal stimuli, and this irritability plays a pivotal role in nature. Inspired by such natural …

A universal lesion detection method based on partially supervised learning

X Wang, X Shi, X Meng, Z Zhang… - Frontiers in Pharmacology, 2023 - frontiersin.org
Partially supervised learning (PSL) is urgently necessary to explore to construct an efficient
universal lesion detection (ULD) segmentation model. An annotated dataset is crucial but …

Multifunctional Exo III-assisted scalability strategy for constructing DNA molecular logic circuits

C Zeng, X Liu, B Wang, R Qin, Q Zhang - Analyst, 2023 - pubs.rsc.org
The construction of logic circuits is critical to DNA computing. Simple and effective scalability
methods have been the focus of attention in various fields related to constructing logic …

Programming DNA Reaction Networks Using Allosteric DNA Hairpins

R Qin, S Cui, X Zhang, P Shi, S Zhou, B Wang - Biomolecules, 2023 - mdpi.com
The construction of DNA reaction networks with complex functions using various methods
has been an important research topic in recent years. Whether the DNA reaction network …