Nanomechanical mapping of soft materials with the atomic force microscope: methods, theory and applications

R Garcia - Chemical Society Reviews, 2020 - pubs.rsc.org
Fast, high-resolution, non-destructive and quantitative characterization methods are needed
to develop materials with tailored properties at the nanoscale or to understand the …

Imaging modes of atomic force microscopy for application in molecular and cell biology

YF Dufrêne, T Ando, R Garcia, D Alsteens… - Nature …, 2017 - nature.com
Atomic force microscopy (AFM) is a powerful, multifunctional imaging platform that allows
biological samples, from single molecules to living cells, to be visualized and manipulated …

[HTML][HTML] Recent advances in sensing the inter-biomolecular interactions at the nanoscale–A comprehensive review of AFM-based force spectroscopy

A Lostao, KS Lim, MC Pallarés, A Ptak… - International journal of …, 2023 - Elsevier
Biomolecular interactions underpin most processes inside the cell. Hence, a precise and
quantitative understanding of molecular association and dissociation events is crucial, not …

High-speed atomic force microscopy and its future prospects

T Ando - Biophysical reviews, 2018 - Springer
Various techniques have been developed and used to investigate how proteins produce
complex biological architectures and phenomena. Among these techniques, high-speed …

Nanorheology of living cells measured by AFM-based force–distance curves

PD Garcia, CR Guerrero, R Garcia - Nanoscale, 2020 - pubs.rsc.org
Mechanobiology aims to establish functional relationships between the mechanical state of
a living a cell and its physiology. The acquisition of force–distance curves with an AFM is by …

[HTML][HTML] Recent progressive use of atomic force microscopy in biomedical applications

U Maver, T Velnar, M Gaberšček, O Planinšek… - TrAC Trends in …, 2016 - Elsevier
In recent years, a great deal of interest has been focused on the development of novel
atomic force microscopy (AFM)-based methods. From first being an unstable method, AFM …

The 2018 correlative microscopy techniques roadmap

T Ando, SP Bhamidimarri, N Brending… - Journal of physics D …, 2018 - iopscience.iop.org
Developments in microscopy have been instrumental to progress in the life sciences, and
many new techniques have been introduced and led to new discoveries throughout the last …

Unraveling the macromolecular pathways of IgG oligomerization and complement activation on antigenic surfaces

J Strasser, RN de Jong, FJ Beurskens, G Wang… - Nano …, 2019 - ACS Publications
IgG antibodies play a central role in protection against pathogens by their ability to alert and
activate the innate immune system. Here, we show that IgGs assemble into oligomers on …

High-speed atomic force microscopy

T Ando - Current opinion in chemical biology, 2019 - Elsevier
High-speed atomic force microscopy (HS-AFM) is a unique tool for molecular imaging. It can
directly visualize protein molecules during their functional activity at high spatiotemporal …

Morphological changes of plasma membrane and protein assembly during clathrin-mediated endocytosis

A Yoshida, N Sakai, Y Uekusa, Y Imaoka, Y Itagaki… - PLoS …, 2018 - journals.plos.org
Clathrin-mediated endocytosis (CME) proceeds through a series of morphological changes
of the plasma membrane induced by a number of protein components. Although the …