The study of regeneration in Drosophila imaginal discs provides an opportunity to use
powerful genetic tools to address fundamental problems pertaining to tissue regeneration …

Dorsal closure is a key process during Drosophila morphogenesis that models cell sheet
movements in chordates, including neural tube closure, palate formation, and wound …

The actin cable is a supracellular structure that embryonic epithelia produce to close gaps.
However, the action of the cable remains debated. Here, we address the function of the …

Understanding the molecular basis of wound healing and regeneration in vertebrates is one
of the main challenges in biology and medicine. This understanding will lead to medical …

Mechanical forces play important roles during tissue organization in developing animals.
Many tissues are organized into adjacent, nonmixing groups of cells termed compartments …

Understanding transdifferentiation—the conversion of one differentiated cell type into
another—is important from both basic science and clinical perspectives. In Caenorhabditis …

Animal tissues are composed of heterogenous cells, and their sorting into different
compartments of the tissue is a pivotal process for organogenesis. Cells accomplish sorting …

While Caenorhabditis elegans was originally regarded as a model for investigating
determinate developmental programs, landmark studies have subsequently shown that the …

The Jun‐N‐terminal Kinase pathway (JNK), known also as stress activated protein kinase
pathway (SAPK), is an eukaryotic evolutionarily conserved signaling pathway. From a …

One of the main topics in regeneration biology is the nature of the early signals that trigger
the damage response. Recent advances in Drosophila point to the MAP3 kinase Ask1 as a …