In the last decades, Candida albicans has served as the leading causal agent of life-
threatening invasive infections with mortality rates approaching 40% despite treatment …

Fungi must meet four criteria to infect humans: growth at human body temperatures,
circumvention or penetration of surface barriers, lysis and absorption of tissue, and …

Thermal adaptation is essential in all organisms. In yeasts, the heat shock response is
commanded by the heat shock transcription factor Hsf1. Here we have integrated unbiased …

Fungal disease is an increasing problem in both agriculture and human health. Treatment of
human fungal disease involves the use of chemical fungicides, which generally target the …

Fusarium avenaceum is a fungus commonly isolated from soil and associated with a wide
range of host plants. We present here three genome sequences of F. avenaceum, one …

Background The gut microbiota plays an important role in human health, as it can affect host
immunity and susceptibility to infectious diseases. Invasive intestinal candidiasis is strongly …

The major fungal pathogen of humans, Candida albicans, mounts robust responses to
oxidative stress that are critical for its virulence. These responses counteract the reactive …

Background Pulmonary arterial hypertension (PAH) is a devastating cardiopulmonary
disorder characterized by elevated pulmonary arterial pressure (PAP) and right ventricular …

Temperature is a ubiquitous environmental variable which can profoundly influence the
physiology of living cells as it changes over time and space. When yeast cells are exposed …

Magnolol, a lignin compound extracted from Magnolia officinalis Cortex, has been found to
have prominent antifungal effects against Candida albicans. However, the specific …