Gestational diabetes mellitus and developmental programming

AHY Chu, KM Godfrey - Annals of Nutrition and Metabolism, 2021 - karger.com
During normal pregnancy, increased insulin resistance acts as an adaptation to enhance
materno-foetal nutrient transfer and meet the nutritional needs of the developing foetus …

Gestational diabetes mellitus and maternal immune dysregulation: what we know so far

CJ McElwain, FP McCarthy, CM McCarthy - International Journal of …, 2021 - mdpi.com
Gestational diabetes mellitus (GDM) is an obstetric complication that affects approximately 5–
10% of all pregnancies worldwide. GDM is defined as any degree of glucose intolerance …

The role of environmental exposures in atopic dermatitis

S Narla, JI Silverberg - Current allergy and asthma reports, 2020 - Springer
Abstract Purpose of Review Although genetic factors clearly play a role in the development
of atopic dermatitis (AD), the recent dramatic increase in the prevalence of AD in low-and …

Gestational diabetes augments group B Streptococcus infection by disrupting maternal immunity and the vaginal microbiota

V Mercado-Evans, ME Mejia, JJ Zulk, S Ottinger… - Nature …, 2024 - nature.com
Abstract Group B Streptococcus (GBS) is a pervasive perinatal pathogen, yet factors driving
GBS dissemination in utero are poorly defined. Gestational diabetes mellitus (GDM), a …

New prebiotics by ketone donation

T Satoh - Trends in Endocrinology & Metabolism, 2023 - cell.com
Integrity of the microbiome is an essential element for human gut health. 3-Hydroxybutyrate
(3HB) secreted into the gut lumen has gained attention as a regulator of gut physiology …

Dynamic changes in regulatory T cells during normal pregnancy, recurrent pregnancy loss, and gestational diabetes

W Wang, Y Zhao, X Zhou, N Sung, L Chen… - Journal of reproductive …, 2022 - Elsevier
Regulatory T cells (Tregs) are critical to regulating maternal T-cell activation against
trophoblast; however, the characteristics of maternal Tregs during pregnancy have not been …

Periodontitis and gestational diabetes mellitus: a potential inflammatory vicious cycle

MJ Bendek, G Canedo-Marroquín, O Realini… - International Journal of …, 2021 - mdpi.com
Periodontitis is a chronic inflammatory immune disease associated with a dysbiotic state,
influenced by keystone bacterial species responsible for disrupting the periodontal tissue …

Arsenic induces continuous inflammation and regulates Th1/Th2/Th17/Treg balance in liver and kidney in vivo

X Duan, G Xu, J Li, N Yan, X Li, X Liu… - Mediators of …, 2022 - Wiley Online Library
Numerous studies on arsenic‐induced hepatonephric toxicity including cancer have been
reported. Given that chronic inflammatory response and immune imbalance are associated …

Plasma cytokines during pregnancy provide insight into the risk of diabetes in the gestational diabetes risk group

A Tagoma, K Haller‐Kikkatalo, A Oras… - Journal of Diabetes …, 2022 - Wiley Online Library
ABSTRACT Aims/Introduction Gestational diabetes (GDM) is characterized by low‐grade
systemic inflammation, which manifests as changes in the levels of cytokines in the blood …

Pregnancy immune tolerance at the maternal-fetal interface

X Li, J Zhou, M Fang, B Yu - International Reviews of Immunology, 2020 - Taylor & Francis
Pregnancy is a natural process that poses an immunological challenge because non-self
fetus must be accepted. During the pregnancy period, the fetus as 'allograft'inherits maternal …