Infectious diseases, along with cancers, are among the main causes of death among
humans worldwide. The production of therapeutic proteins for treating diseases at large …

Recombinant proteins have been produced for over 30 years. Applications range from
enzymes used in laundry detergents to antigen-detecting antibodies in cancer therapy …

Extracellular vesicles (EVs) are membranous nanovesicles secreted from living cells,
shuttling macromolecules in intercellular communication and potentially possessing intrinsic …

The use of biopharmaceuticals dates from the 19th century and within 5-10 years, up to 50%
of all drugs in development will be biopharmaceuticals. In the 1980s, the biopharmaceutical …

Escherichia coli is the most widely used heterologous protein expression system. However,
this system remains a challenge due to the low solubility of proteins, insufficient yield, and …

Recombinant proteins are produced for various applications in laboratory and industrial
settings. Among them, therapeutic applications have evolved into a mature field in recent …

The use of strong magnetic field gradients and high magnetic fields generated by permanent
magnets or superconducting coils has found applications in many fields such as mining …

Epitope imprinting is a promising tool to generate antibody‐like specific recognition sites.
Recently, because of the ease of obtaining templates, the flexibility in selecting monomers …

Endotoxins are the major contributors to the pyrogenic response caused by contaminated
pharmaceutical products, formulation ingredients, and medical devices. Recombinant …

Purified protein quality control is the final and critical check-point of any protein production
process. Unfortunately, it is too often overlooked and performed hastily, resulting in …