Regulatory Mechanisms of Aging Through the Nutritional and Metabolic Control of Amino Acid Signaling in Model Organisms
F Obata, M Miura - Annual Review of Genetics, 2024 - annualreviews.org
Life activities are supported by the intricate metabolic network that is fueled by nutrients.
Nutritional and genetic studies in model organisms have determined that dietary restriction …
Nutritional and genetic studies in model organisms have determined that dietary restriction …
Dissecting the oncogenic properties of essential RNA-modifying enzymes: a focus on NAT10
Chemical modifications of ribonucleotides significantly alter the physicochemical properties
and functions of RNA. Initially perceived as static and essential marks in ribosomal RNA …
and functions of RNA. Initially perceived as static and essential marks in ribosomal RNA …
Pathogenic tau induces an adaptive elevation in mRNA translation rate at early stages of disease
Alterations in the rate and accuracy of messenger RNA (mRNA) translation are associated
with aging and several neurodegenerative disorders, including Alzheimer's disease and …
with aging and several neurodegenerative disorders, including Alzheimer's disease and …
Gut-to-brain regulation of Drosophila aging through neuropeptide F, insulin, and juvenile hormone
Dietary restriction (DR) slows aging in many animals, while in some cases, the sensory
signals from diet alone are sufficient to retard or accelerate lifespan. The digestive tract is a …
signals from diet alone are sufficient to retard or accelerate lifespan. The digestive tract is a …
Feeding a rich diet supplemented with the translation inhibitor cycloheximide decreases lifespan and ovary size in Drosophila
HJ Hwang, RT Cox - Biology Open, 2024 - journals.biologists.com
Drosophila oogenesis has long been an important model for understanding myriad cellular
processes controlling development, RNA biology and patterning. Flies are easily fed drugs …
processes controlling development, RNA biology and patterning. Flies are easily fed drugs …
Targeting eIF2α in TBI-induced traumatic optic neuropathy: Effects of Salubrinal and the Integrated Stress Response Inhibitor.
S Hetzer, R Bellary, JN Torrens, RF Grimaldi… - bioRxiv, 2024 - biorxiv.org
Traumatic brain injury (TBI) can induce traumatic axonal injury in the optic nerve, which is
referred to as traumatic optic neuropathy (TON). TON occurs in up to 5% of TBI cases and …
referred to as traumatic optic neuropathy (TON). TON occurs in up to 5% of TBI cases and …
The adolescent and the axon: Assessing the role of the ER in a murine model of traumatic optic neuropathy
SM Hetzer - 2024 - search.proquest.com
Traumatic brain injury (TBI) is an incredibly heterogenous pathology, yet many of the current
mechanisms under exploration involve a common phenotype, traumatic axonal injury (TAI) …
mechanisms under exploration involve a common phenotype, traumatic axonal injury (TAI) …
[引用][C] Protein translation rates are negatively correlated with lifespan in in-bred Drosophila strains
HS Kim, MM Hardiman… - The Journals of …, 2024 - academic.oup.com
Protein translation (PT) is an essential cellular process that plays critical roles in growth and
development. PT occurs at high levels in early adulthood but declines with age across …
development. PT occurs at high levels in early adulthood but declines with age across …