Dangerous Liaisons: Interactions of Cryptococcus neoformans with Host Phagocytes

EA Gaylord, HL Choy, TL Doering - Pathogens, 2020 - mdpi.com
Cryptococcus neoformans is an opportunistic fungal pathogen and a leading cause of death
in immunocompromised individuals. The interactions of this yeast with host phagocytes are …

Antibacterial activities of anthraquinones: structure–activity relationships and action mechanisms

T Qun, T Zhou, J Hao, C Wang, K Zhang, J Xu… - RSC Medicinal …, 2023 - pubs.rsc.org
With the increasing prevalence of untreatable infections caused by antibiotic-resistant
bacteria, the discovery of new drugs from natural products has become a hot research topic …

A novel protocol for the isolation of fungal extracellular vesicles reveals the participation of a putative scramblase in polysaccharide export and capsule construction in …

FCG Reis, BS Borges, LJ Jozefowicz, BAG Sena… - MSphere, 2019 - Am Soc Microbiol
Regular protocols for the isolation of fungal extracellular vesicles (EVs) are time-consuming,
hard to reproduce, and produce low yields. In an attempt to improve the protocols used for …

Exploitation of the antifungal and antibiofilm activities of plumbagin against Cryptococcus neoformans

W Qian, W Wang, J Zhang, Y Fu, Q Liu, X Li, T Wang… - Biofouling, 2022 - Taylor & Francis
Cryptococcus neoformans is an important opportunistic fungal pathogen that causes various
infections. Here, the antifungal and antibiofilm activities of plumbagin against C. neoformans …

Phenotypic characteristics and transcriptome profile of Cryptococcus gattii biofilm

ER Tavares, B Gionco, AEB Morguette, GM Andriani… - Scientific Reports, 2019 - nature.com
In this study, we characterized Cryptococcus gattii biofilm formation in vitro. There was an
increase in the density of metabolically active sessile cells up to 72 h of biofilm formation on …

Synergistic antifungal interaction of N-(butylcarbamothioyl) benzamide and amphotericin B against Cryptococcus neoformans

GM Andriani, LFA Spoladori, M Fabris… - Frontiers in …, 2023 - frontiersin.org
Introduction Cryptococcus neoformans is one of the leading causes of invasive fungal
infections worldwide. Cryptococcal meningoencephalitis is the main challenge of antifungal …

Cell Adhesion, Elasticity, and Rupture Forces Guide Microbial Cell Death on Nanostructured Antimicrobial Titanium Surfaces

LZY Huang, ZL Shaw, R Penman… - ACS Applied Bio …, 2023 - ACS Publications
Naturally occurring and synthetic nanostructured surfaces have been widely reported to
resist microbial colonization. The majority of these studies have shown that both bacterial …

[HTML][HTML] Antifungal combination of ethyl acetate extract of Poincianella pluviosa (DC.) LP queiros stem bark with amphotericin B in Cryptococcus neoformans

GM Andriani, AEB Morguette, LFA Spoladori… - Frontiers in …, 2021 - frontiersin.org
Cryptococcus neoformans is the leading cause of cryptococcosis, an invasive and
potentially fatal infectious disease. Therapeutic failures are due to the increase in antifungal …

Antifungal activity of promethazine and chlorpromazine against planktonic cells and biofilms of Cryptococcus neoformans/Cryptococcus gattii complex species

RSN Brilhante, WJP Gotay, VS Pereira… - Medical …, 2020 - academic.oup.com
Cryptococcus neoformans/Cryptococcus gattii are fungal pathogens that affect the central
nervous system, mainly in immunocompromised individuals. Due to the limited …

Phenotypic characterization of HAM1, a novel mating regulator of the fungal pathogen Cryptococcus neoformans

E Arsenault Yee, RL Ross… - Microbiology …, 2024 - Am Soc Microbiol
Cryptococcus neoformans is a fungal pathogen responsible for> 200,000 yearly cases with
a mortality as high as 81%. This burden results, in part, from an incomplete understanding of …