Inflammation: roles in skeletal muscle atrophy
Y Ji, M Li, M Chang, R Liu, J Qiu, K Wang, C Deng… - Antioxidants, 2022 - mdpi.com
Various diseases can cause skeletal muscle atrophy, usually accompanied by inflammation,
mitochondrial dysfunction, apoptosis, decreased protein synthesis, and enhanced …
mitochondrial dysfunction, apoptosis, decreased protein synthesis, and enhanced …
Glucocorticoid-induced skeletal muscle atrophy
O Schakman, S Kalista, C Barbé, A Loumaye… - The international journal …, 2013 - Elsevier
Many pathological states characterized by muscle atrophy (eg, sepsis, cachexia, starvation,
metabolic acidosis and severe insulinopenia) are associated with an increase in circulating …
metabolic acidosis and severe insulinopenia) are associated with an increase in circulating …
Signaling pathways controlling skeletal muscle mass
MA Egerman, DJ Glass - Critical reviews in biochemistry and …, 2014 - Taylor & Francis
The molecular mechanisms underlying skeletal muscle maintenance involve interplay
between multiple signaling pathways. Under normal physiological conditions, a network of …
between multiple signaling pathways. Under normal physiological conditions, a network of …
[HTML][HTML] Mechanisms regulating neuromuscular junction development and function and causes of muscle wasting
LA Tintignac, HR Brenner… - Physiological …, 2015 - journals.physiology.org
The neuromuscular junction is the chemical synapse between motor neurons and skeletal
muscle fibers. It is designed to reliably convert the action potential from the presynaptic …
muscle fibers. It is designed to reliably convert the action potential from the presynaptic …
The ubiquitin–proteasome system in regulation of the skeletal muscle homeostasis and atrophy: from basic science to disorders
Y Kitajima, K Yoshioka, N Suzuki - The Journal of Physiological Sciences, 2020 - Springer
Skeletal muscle is one of the most abundant and highly plastic tissues. The ubiquitin–
proteasome system (UPS) is recognised as a major intracellular protein degradation system …
proteasome system (UPS) is recognised as a major intracellular protein degradation system …
Polyphenols and their effects on muscle atrophy and muscle health
T Nikawa, A Ulla, I Sakakibara - Molecules, 2021 - mdpi.com
Skeletal muscle atrophy is the decrease in muscle mass and strength caused by reduced
protein synthesis/accelerated protein degradation. Various conditions, such as denervation …
protein synthesis/accelerated protein degradation. Various conditions, such as denervation …
The role and regulation of MAFbx/atrogin-1 and MuRF1 in skeletal muscle atrophy
VC Foletta, LJ White, AE Larsen, B Léger… - … -European Journal of …, 2011 - Springer
Skeletal muscle atrophy occurs in many chronic diseases and disuse conditions. Its severity
reduces patient recovery, independence and quality of life. The discovery of two muscle …
reduces patient recovery, independence and quality of life. The discovery of two muscle …
Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders
Insulin resistance is a fundamental pathogenic factor present in various metabolic disorders
including obesity and type 2 diabetes. Although skeletal muscle accounts for 70–90% of …
including obesity and type 2 diabetes. Although skeletal muscle accounts for 70–90% of …
Regional neural activation defines a gateway for autoreactive T cells to cross the blood-brain barrier
Y Arima, M Harada, D Kamimura, JH Park, F Kawano… - Cell, 2012 - cell.com
Although it is believed that neural activation can affect immune responses, very little is
known about the neuroimmune interactions involved, especially the regulators of immune …
known about the neuroimmune interactions involved, especially the regulators of immune …
Metabolic functions of glucocorticoid receptor in skeletal muscle
Glucocorticoids (GCs) exert key metabolic influences on skeletal muscle. GCs increase
protein degradation and decrease protein synthesis. The released amino acids are …
protein degradation and decrease protein synthesis. The released amino acids are …