Arsenic, cadmium, nickel and hexavalent chromium are among the most common
environmental pollutants and potent carcinogens. Chronic exposure to these metals causes …

A number of metals are toxic and carcinogenic to humans. Reactive oxygen species (ROS)
play an important role in metal carcinogenesis. Oxidative stress acts as the converging point …

Circular RNAs (circRNAs) are involved in cancer development via inhibition of miRNAs,
which are associated with differentiation, proliferation, migration, and carcinogenicity …

Production of nickel (Ni) and nickel oxide (NiO) nanoparticles (NPs) leads to a risk of
exposure and subsequent health effects. Understanding the toxicological effects and …

Oral squamous cell carcinoma (OSCC), one of the most deadliest malignancies in the world,
is caused primarily by areca nut chewing in Southeast Asia. The mechanisms by which …

Cadmium (Cd) is a well-known lung carcinogen. However, the mechanism of Cd
carcinogenesis remains to be clearly defined. Cd has been shown to act as a weak …

In vitro transformation assays not only serve practical purposes in screening for potential
carcinogenic substances in food, drug, and cosmetic industries, but more importantly, they …

Human beings are exposed to carcinogens through air, water, food and tobacco smoke.
Nickel chloride (NiCl2) is a toxic and carcinogenic environmental and occupational …

肺癌是全球致死率最高的肿瘤, 耐药和复发是肺癌致死率居高不下的关键原因之一.
大量研究证据表明, 在肺癌组织和细胞中存在一小群具有干性样特征的细胞 …

Cancer stem cells (CSCs) are immortal cells in tumor tissues that have been proposed as
the driving force of tumorigenesis and tumor invasion. Previously, ion channels were …