Copper (Cu) is an essential micronutrient involved in a variety of fundamental biological
processes. Recently, disorder of Cu homeostasis can be observed in many malignancies …

Metallothioneins (MTs) are small cysteine-rich proteins that play important roles in metal
homeostasis and protection against heavy metal toxicity, DNA damage, and oxidative stress …

Copper ions are needed in several steps of cancer progression. However, the underlying
mechanisms, and involved copper-binding proteins, are mainly elusive. Since most copper …

Metallothioneins (MTs) are essential mammalian metal chaperones. MT isoform 1 (MT1) is
expressed in the kidneys and isoform 3 (MT3) is expressed in nervous tissue. For MTs, the …

Breast cancer has become the most common cancer worldwide. Despite the major
advances made in the past few decades in the treatment of breast cancer using a …

Abstract DBTSS (Database of Transcriptional Start Sites)/DBKERO (Database of Kashiwa
Encyclopedia for human genome mutations in Regulatory regions and their Omics contexts) …

Metallothioneins (MTs) are low molecular weight proteins, which are present in almost all
types of organisms. In mammals, four main MT isoforms designated from MT-1 to MT-4 were …

Background Tumor metastasis is an essential cause of the poor prognosis of colon cancer.
DC-SIGNR is a C-type lectin that is frequently found on human liver sinusoidal endothelial …

Metallothionein-3 has poorly characterized functions in neuroblastoma. Cisplatin-based
chemotherapy is a major regimen to treat neuroblastoma, but its clinical efficacy is limited by …

Aims Fibroblast growth factor 21 (FGF 21) acts as a metabolic regulator and exerts
cardioprotective effects. However, the effects of long‐term FGF 21 administration on the …