Enzymes, In Vivo Biocatalysis, and Metabolic Engineering for Enabling a Circular Economy and Sustainability

P Intasian, K Prakinee, A Phintha, D Trisrivirat… - Chemical …, 2021 - ACS Publications
Since the industrial revolution, the rapid growth and development of global industries have
depended largely upon the utilization of coal-derived chemicals, and more recently, the …

Application of combinatorial optimization strategies in synthetic biology

G Naseri, MAG Koffas - Nature communications, 2020 - nature.com
In the first wave of synthetic biology, genetic elements, combined into simple circuits, are
used to control individual cellular functions. In the second wave of synthetic biology, the …

[HTML][HTML] Enzymes revolutionize the bioproduction of value-added compounds: From enzyme discovery to special applications

B Wiltschi, T Cernava, A Dennig, MG Casas… - Biotechnology …, 2020 - Elsevier
Competitive sustainable production in industry demands new and better biocatalysts,
optimized bioprocesses and cost-effective product recovery. Our review sheds light on the …

DCEO biotechnology: tools to design, construct, evaluate, and optimize the metabolic pathway for biosynthesis of chemicals

X Chen, C Gao, L Guo, G Hu, Q Luo, J Liu… - Chemical …, 2018 - ACS Publications
Chemical synthesis is a well established route for producing many chemicals on a large
scale, but some drawbacks still exist in this process, such as unstable intermediates …

Engineered methanotrophy: a sustainable solution for methane-based industrial biomanufacturing

AD Nguyen, EY Lee - Trends in Biotechnology, 2021 - cell.com
Methane is a promising feedstock with high abundance and low cost for the sustainable
production of biochemicals and biofuels. Methanotrophic bacteria are particularly interesting …

Microbial Platform for Terpenoid Production: Escherichia coli and Yeast

C Wang, M Liwei, JB Park, SH Jeong, G Wei… - Frontiers in …, 2018 - frontiersin.org
Terpenoids, also called isoprenoids, are a large and highly diverse family of natural
products with important medical and industrial properties. However, a limited production of …

[HTML][HTML] Adaptive strategies of the candidate probiotic E. coli Nissle in the mammalian gut

N Crook, A Ferreiro, AJ Gasparrini, MW Pesesky… - Cell host & …, 2019 - cell.com
Probiotics are living microorganisms that are increasingly used as gastrointestinal
therapeutics by virtue of their innate or engineered genetic function. Unlike abiotic …

Alternative Watson–Crick synthetic genetic systems

SA Benner, NB Karalkar, S Hoshika… - Cold Spring …, 2016 - cshperspectives.cshlp.org
In its “grand challenge” format in chemistry,“synthesis” as an activity sets out a goal that is
substantially beyond current theoretical and technological capabilities. In pursuit of this goal …

Metabolic engineering for the production of acetoin and 2,3-butanediol at elevated temperature in Parageobacillus thermoglucosidasius NCIMB 11955

L Sheng, A Madika, MSH Lau, Y Zhang… - … in Bioengineering and …, 2023 - frontiersin.org
The current climate crisis has emphasised the need to achieve global net-zero by 2050, with
countries being urged to set considerable emission reduction targets by 2030. Exploitation …

Challenges and tackles in metabolic engineering for microbial production of carotenoids

C Wang, S Zhao, X Shao, JB Park, SH Jeong… - Microbial Cell …, 2019 - Springer
Naturally occurring carotenoids have been isolated and used as colorants, antioxidants,
nutrients, etc. in many fields. There is an ever-growing demand for carotenoids production …