Female sex, a major risk factor for salt-sensitive hypertension
JL Faulkner, EJ Belin de Chantemèle - Current hypertension reports, 2020 - Springer
Abstract Purpose of Review High dietary salt is a significant contributor to essential
hypertension in clinical populations. However, although clinical studies indicate a higher …
hypertension in clinical populations. However, although clinical studies indicate a higher …
mTOR in metabolic homeostasis and disease
X Liu, B Guo, Q Li, J Nie - Experimental cell research, 2024 - Elsevier
The ability to maintain cellular metabolic homeostasis is critical to life, in which mTOR plays
an important role. This kinase integrates upstream nutrient signals and performs essential …
an important role. This kinase integrates upstream nutrient signals and performs essential …
Biological sex modifies aldosterone's secretion at a cellular level
SK Gholami, CS Tay, JM Lee, E Zagoren… - Journal of …, 2022 - joe.bioscientifica.com
Inconsistencies have been reported on the effect of sex on aldosterone levels leading to
clinical confusion. The reasons for these inconsistencies, are uncertain but include: estrogen …
clinical confusion. The reasons for these inconsistencies, are uncertain but include: estrogen …
[HTML][HTML] Renal Inflammation, Oxidative Stress, and Metabolic Abnormalities During the Initial Stages of Hypertension in Spontaneously Hypertensive Rats
P Wojtacha, E Bogdańska-Chomczyk, MK Majewski… - Cells, 2024 - pmc.ncbi.nlm.nih.gov
Background: Hypertension is a major cause of mortality worldwide. The kidneys play a
crucial role in regulating blood pressure and fluid volume. The relationship between the …
crucial role in regulating blood pressure and fluid volume. The relationship between the …
Role of Raptor Gene Variants in Hypertension: Influence on Blood Pressure Independent of Salt Intake in White Population
BACKGROUND: The mTOR (mechanistic target of rapamycin) is an essential regulator of
fundamental biological processes. mTOR forms 2 distinct complexes, mTORC1 (mTOR …
fundamental biological processes. mTOR forms 2 distinct complexes, mTORC1 (mTOR …
Lysine-specific demethylase 1 deficiency modifies aldosterone synthesis in a sex-specific manner
YJD Tan, DL Brooks, KYH Wong… - Journal of …, 2023 - joe.bioscientifica.com
Biologic sex influences the development of cardiovascular disease and modifies
aldosterone (ALDO) and blood pressure (BP) phenotypes: females secrete more ALDO, and …
aldosterone (ALDO) and blood pressure (BP) phenotypes: females secrete more ALDO, and …