[HTML][HTML] 2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implications

N Gonzalez, I Prieto, L del Puerto-Nevado… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Worldwide deaths from diabetes mellitus (DM) and colorectal cancer increased by 90% and
57%, respectively, over the past 20 years. The risk of colorectal cancer was estimated to be …

Role of telomeres and associated maintenance genes in Type 2 Diabetes Mellitus: A review

I Sethi, GR Bhat, V Singh, R Kumar… - Diabetes research and …, 2016 - Elsevier
Abstract Type 2 Diabetes Mellitus (T2 DM), a multifactorial complex disorder, is emerging as
a major cause of morbidity, mortality and socio-economic burden across the world. Despite …

Cohort profile: genetics of diabetes audit and research in Tayside Scotland (GoDARTS)

HL Hébert, B Shepherd, K Milburn… - International journal …, 2018 - academic.oup.com
The prevalence of diabetes worldwide has been steadily increasing over the past 20 years.
In 1997 it was estimated to be 124 million, 1 in 2015 it was estimated to be 415 million …

[HTML][HTML] Circ-ACTR2 aggravates the high glucose-induced cell dysfunction of human renal mesangial cells through mediating the miR-205-5p/HMGA2 axis in diabetic …

J Yun, J Ren, Y Liu, L Dai, L Song, X Ma, S Luo… - Diabetology & metabolic …, 2021 - Springer
Abstract Background Circular RNAs (circRNAs) have been considered as pivotal biomarkers
in Diabetic nephropathy (DN). CircRNA ARP2 actin-related protein 2 homolog (circ-ACTR2) …

KCNQ1OT1/miR-18b/HMGA2 axis regulates high glucose-induced proliferation, oxidative stress, and extracellular matrix accumulation in mesangial cells

J Li, M Li, L Bai - Molecular and cellular biochemistry, 2021 - Springer
The dysregulated long noncoding RNAs (lncRNAs) are associated with the pathogenesis of
diabetic nephropathy (DN). LncRNA potassium voltage-gated channel subfamily Q member …

[HTML][HTML] miR-98-5p alleviated epithelial-to-mesenchymal transition and renal fibrosis via targeting Hmga2 in diabetic nephropathy

Y Zhu, J Xu, W Liang, J Li, L Feng, PX Zheng… - International Journal of …, 2019 - hindawi.com
Recently, microRNAs have been recognized as crucial regulators of diabetic nephropathy
(DN) development. Epithelial-to-mesenchymal transition (EMT) can play a significant role in …

[HTML][HTML] Long non-coding RNAs in the pathogenesis of diabetic kidney disease

M Hu, Q Ma, B Liu, Q Wang, T Zhang… - Frontiers in Cell and …, 2022 - frontiersin.org
Diabetic kidney disease (DKD) is one of the major microvascular complications of diabetes
mellitus, with relatively high morbidity and mortality globally but still in-short therapeutic …

AT-hook peptides bind the major and minor groove of AT-rich DNA duplexes

A Garabedian, K Jeanne Dit Fouque… - Nucleic Acids …, 2022 - academic.oup.com
The mammalian high mobility group protein AT-hook 2 (HMGA2) houses three motifs that
preferentially bind short stretches of AT-rich DNA regions. These DNA binding motifs, known …

Association of rs11643718 SLC12A3 and rs741301 ELMO1 Variants with Diabetic Nephropathy in South Indian Population

D Bodhini, M Chidambaram, S Liju… - Annals of human …, 2016 - Wiley Online Library
This study reports on the association of genetic variants selected from previous genome‐
wide association studies for type 2 diabetic nephropathy in south Indians. Eight variants …

Serum fibrinogen predicts diabetic ESRD in patients with type 2 diabetes mellitus

J Zhang, Y Wang, R Zhang, H Li, Q Han, Y Wu… - Diabetes Research and …, 2018 - Elsevier
Aims Although increased serum fibrinogen level was often observed in patients with diabetic
nephropathy (DN), its association with DN severity and progression remains unclear. The …