Abstract MCP-1 (Monocyte chemoattractant protein-1), also known as Chemokine (CC-motif)
ligand 2 (CCL2), is from family of CC chemokines. It has a vital role in the process of …

Acute and acute-on-chronic liver failure (ALF and ACLF), though distinct clinical entities, are
considered syndromes of innate immune dysfunction. Patients with ALF and ACLF display …

Chemokines are a family of cytokines that orchestrate the migration and positioning of
immune cells within tissues and are critical for the function of the immune system. CCR2 …

The complex functions of the liver in biosynthesis, metabolism, clearance, and host defense
are tightly dependent on an adequate microcirculation. To guarantee hepatic homeostasis …

Chemokines and chemokine receptors contribute to the migration of hepatic stellate cells
(HSCs) and Kupffer cells, two key cell types in fibrogenesis. Here, we investigate the role of …

Reactive oxygen species (ROS) generated within cells or, more generally, in a tissue
environment, may easily turn into a source of cell and tissue injury. Aerobic organisms have …

The importance of chemokines in alcoholic liver injury has been implicated. The role of the
chemokine, monocyte chemoattractant protein‐1 (MCP‐1), elevated in patients with …

Rationale: Mitochondrial oxidative stress (mitoOS) has been shown to correlate with the
progression of human atherosclerosis. However, definitive cell type–specific causation …

Different etiologies such as drug toxicity, acute viral hepatitis B, or acetaminophen poisoning
can cause acute liver injury or even acute liver failure (ALF). Excessive cell death of …

Long term hepatitis B virus (HBV) infection is a major risk factor in pathogenesis of chronic
liver diseases, including hepatocellular carcinoma (HCC). The HBV encoded proteins …