Moderately elevated plasma total homocysteine (tHcy) is a strong modifiable risk factor for
vascular dementia and Alzheimer's disease. Prospectively, elevated tHcy is associated with …

The recent increase in the intake of folic acid by the general public through fortified foods
and supplements, has raised safety concern based on early reports of adverse health …

Folate is a vital component of a healthy diet, being essential for numerous bodily functions.
Deficiency of folate is common, with studies suggesting prevalence of deficiencyas high as …

Background & aims Mild cognitive impairment (MCI) patients are at risk of cognitive decline,
while elevated serum homocysteine is also associated with cognitive impairment. Thus …

Micronutrient deficiencies occur in segments of the adult population in the United States.
Multivitamin/multimineral supplements (MVMS) are widely used by this population, which …

The key to preventing brain aging, mild cognitive impairment (MCI), and Alzheimer disease
(AD) via vitamin intake is first to understand molecular mechanisms, then to deduce relevant …

Folic acid (FA), a water-soluble vitamin (B9), is crucial for metabolic activities and regulatory
processes of cells. Mammalian cells cannot synthesize any form of folate, thereby …

Neural tube defects (NTDs) are the second most common congenital malformations of
humans, characterized by impaired development of the central nervous system. Even …

Background Studies on the association between folate/folic acid exposure and the
development of allergic disease have yielded inconsistent results, which may be due, in …

Folate is an essential nutrient for growth in early life. This study aimed to determine the
levels and compositions of folate in Chinese breast milk samples. This study was part of the …