Gut-on-a-Chip Models: Current and Future Perspectives for HostMicrobial Interactions Research

M Morelli, D Kurek, CP Ng, K Queiroz - Biomedicines, 2023 - mdpi.com
The intestine contains the largest microbial community in the human body, the gut
microbiome. Increasing evidence suggests that it plays a crucial role in maintaining overall …

Modeling gut neuro-epithelial connections in a novel microfluidic device

JM de Hoyos-Vega, X Yu… - Microsystems & …, 2023 - nature.com
The intestinal lumen is filled with diverse chemical and physical stimuli. Intestinal epithelial
cells sense these stimuli and signal to enteric neurons which coordinate a range of …

[HTML][HTML] Modeling Gut Neuro-Epithelial Connections in a Novel Micro uidic Device

M De Hoyos, X Yu, A Gonzalez-Suarez… - Research …, 2023 - ncbi.nlm.nih.gov
Organs that face external environments, such as skin and gut, are lined by epithelia, which
have two functions–to provide a semi-permeable barrier and to sense stimuli. The intestinal …

Design and simulation study of organ-on-a-chip

S Amir, S Reshma, MJA Krishnan, X Joseph… - Human Organs-on-a …, 2024 - Elsevier
Basic and advanced research in the field of science and engineering has always been
interconnected by supporting each other. The interdisciplinary nature of approaching …

CFD Investigation into Influences of a Transversely and Periodically Deforming Microchannel on Shear Stress Behavior in a Gut-on-a-chip Device

P Borwornpiyawat, E Juntasaro, S Aueviriyavit… - Engineering …, 2023 - engj.org
Organ-on-a-chip allows dynamic microenvironment of the actual organ to be simulated in
vitro. In this study, the CFD simulation is used to investigate the behaviors of fluid flow and …