Beyond assembly: the increasing flexibility of single-molecule sequencing technology
The maturation of high-throughput short-read sequencing technology over the past two
decades has shaped the way genomes are studied. Recently, single-molecule, long-read …
decades has shaped the way genomes are studied. Recently, single-molecule, long-read …
Agnostic sequencing for detection of viral pathogens
NPG Gauthier, SD Chorlton, M Krajden… - Clinical microbiology …, 2023 - Am Soc Microbiol
The advent of next-generation sequencing (NGS) technologies has expanded our ability to
detect and analyze microbial genomes and has yielded novel molecular approaches for …
detect and analyze microbial genomes and has yielded novel molecular approaches for …
Nanopore long-read-only metagenomics enables complete and high-quality genome reconstruction from mock and complex metagenomes
Background The accurate and comprehensive analyses of genome-resolved metagenomics
largely depend on the reconstruction of reference-quality (complete and high-quality) …
largely depend on the reconstruction of reference-quality (complete and high-quality) …
A signal processing and deep learning framework for methylation detection using Oxford Nanopore sequencing
Oxford Nanopore sequencing can detect DNA methylations from ionic current signal of
single molecules, offering a unique advantage over conventional methods. Additionally …
single molecules, offering a unique advantage over conventional methods. Additionally …
The skin microbiome: current landscape and future opportunities
P Smythe, HN Wilkinson - International journal of molecular sciences, 2023 - mdpi.com
Our skin is the largest organ of the body, serving as an important barrier against the harsh
extrinsic environment. Alongside preventing desiccation, chemical damage and …
extrinsic environment. Alongside preventing desiccation, chemical damage and …
[HTML][HTML] Current concepts, advances, and challenges in deciphering the human microbiota with metatranscriptomics
T Ojala, AE Häkkinen, E Kankuri, M Kankainen - Trends in Genetics, 2023 - cell.com
Metatranscriptomics refers to the analysis of the collective microbial transcriptome of a
sample. Its increased utilization for the characterization of human-associated microbial …
sample. Its increased utilization for the characterization of human-associated microbial …
Data Storage Using DNA
The exponential growth of global data has outpaced the storage capacities of current
technologies, necessitating innovative storage strategies. DNA, as a natural medium for …
technologies, necessitating innovative storage strategies. DNA, as a natural medium for …
Portable nanopore-sequencing technology: Trends in development and applications
P Chen, Z Sun, J Wang, X Liu, Y Bai, J Chen… - Frontiers in …, 2023 - frontiersin.org
Sequencing technology is the most commonly used technology in molecular biology
research and an essential pillar for the development and applications of molecular biology …
research and an essential pillar for the development and applications of molecular biology …
Efficient real-time selective genome sequencing on resource-constrained devices
Background Third-generation nanopore sequencers offer selective sequencing or “Read
Until” that allows genomic reads to be analyzed in real time and abandoned halfway if not …
Until” that allows genomic reads to be analyzed in real time and abandoned halfway if not …
Combination of whole genome sequencing and metagenomics for microbiological diagnostics
Whole genome sequencing (WGS) provides the highest resolution for genome-based
species identification and can provide insight into the antimicrobial resistance and virulence …
species identification and can provide insight into the antimicrobial resistance and virulence …