The midbrain dopamine (mDA) system is composed of molecularly and functionally distinct
neuron subtypes that mediate specific behaviours and are linked to various brain diseases …

Social behavior is naturally occurring in vertebrate species, which holds a strong
evolutionary component and is crucial for the normal development and survival of …

Although the cerebellum is traditionally known for its role in motor functions, recent evidence
points toward the additional involvement of the cerebellum in an array of non-motor …

Among the central goals of stress neurobiology research is to understand the mechanisms
by which stressors change neural circuit function to precipitate or exacerbate psychiatric …

Severe stress exposure increases the risk of stress-related disorders such as major
depressive disorder (MDD). An essential characteristic of MDD is the impairment of social …

There are several hypotheses concerning the underlying pathophysiological mechanisms of
major depression, which centre largely around adaptive changes in neuronal transmission …

The Insula functions as a multisensory relay involved in socio-emotional processing with
projections to sensory, cognitive, emotional, and motivational regions. Notably, the …

To make adaptive decisions, we build an internal model of the associative relationships in
an environment and use it to make predictions and inferences about specific available …

Depression is the second leading cause of disability in the world population, for which
currently available pharmacological therapies either have poor efficacy or have some …

Background Dopaminergic circuits play important roles in the motivational control of
behavior and dysfunction in dopaminergic circuits have been implicated in several …