Angiogenesis is one of the hallmarks of cancer progression and as such has been
considered a target of therapeutic interest. However, single targeted agents have not fully …

Introduction: MicroRNAs (miRNAs) are small endogenous non-coding RNAs that repress the
expression of their target genes by reducing mRNA stability and/or inhibiting translation …

Photodynamic therapy (PDT) has recently gained attention as an alternative treatment of
malignant gliomas. Glioblastoma (GBM) is the most prevalent within tumors of the central …

The immune response against cancer generated by type-I-interferons (IFN-1) has recently
been described. Exogenous and endogenous IFN-α/β have an important role in immune …

Photodynamic therapy is a minimally invasive and clinically approved procedure for
eliminating selected malignant cells with specific light activation of a photosensitizer agent …

Aim: Assess biocompatibility, uptake and photodynamic therapy (PDT) mechanism of
metallated porphyrin doped conjugated polymer nanoparticles (CPNs) in human brain and …

Background Photodynamic therapy (PDT) is a promising new approach to promote wound
healing and its effectiveness has been demonstrated in both clinical and animal studies …

Purpose Previous analyses of the tumor microenvironment (TME) have resulted in a concept
that tumor progression may depend on interactions between cancer cells and its …

Tumor microenvironment (TME) is a dynamic ecosystem where fibroblasts are recruited in
order to provide a niche to support growth and, in some extent, to promote therapeutic …

Purpose The tumor microenvironment (TME) is composed of various stromal components,
including immune cells such as tumor-associated macrophages (TAMs), which play a crucial …