Working memory and executive function decline across normal aging, mild cognitive impairment, and Alzheimer's disease

AM Kirova, RB Bays, S Lagalwar - BioMed research …, 2015 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disease marked by deficits in
episodic memory, working memory (WM), and executive function. Examples of executive …

Meta-analysis of amyloid-cognition relations in cognitively normal older adults

T Hedden, H Oh, AP Younger, TA Patel - Neurology, 2013 - AAN Enterprises
Objective: We conducted a meta-analysis of relationships between amyloid burden and
cognition in cognitively normal, older adult humans. Methods: Methods of assessing amyloid …

The disconnected brain and executive function decline in aging

AM Fjell, MH Sneve, H Grydeland, AB Storsve… - Cerebral …, 2017 - academic.oup.com
Higher order speeded cognitive abilities depend on efficient coordination of activity across
the brain, rendering them vulnerable to age reductions in structural and functional brain …

Dissociating normal aging from Alzheimer's disease: a view from cognitive neuroscience

M Toepper - Journal of Alzheimer's disease, 2017 - content.iospress.com
Both normal aging and Alzheimer's disease (AD) are associated with changes in cognition,
grey and white matter volume, white matter integrity, neural activation, functional …

[HTML][HTML] Cognitive impairment and decline in cognitively normal older adults with high amyloid-β: a meta-analysis

JE Baker, YY Lim, RH Pietrzak, J Hassenstab… - Alzheimer's & dementia …, 2017 - Elsevier
Introduction This meta-analysis aimed to characterize the nature and magnitude of amyloid
(Aβ)-related cognitive impairment and decline in cognitively normal (CN) older individuals …

Functional alignment with anatomical networks is associated with cognitive flexibility

JD Medaglia, W Huang, EA Karuza, A Kelkar… - Nature human …, 2018 - nature.com
Cognitive flexibility describes the human ability to switch between modes of mental function
to achieve goals. Mental switching is accompanied by transient changes in brain activity …

Aging in two languages: Implications for public health

E Bialystok, J Abutalebi, TH Bak, DM Burke… - Ageing research …, 2016 - Elsevier
With the population aging and a dramatic increase in the number of senior citizens, public
health systems will be increasingly burdened with the need to deal with the care and …

Neuropsychological measures predict decline to Alzheimer's dementia from mild cognitive impairment.

MJ Summers, NLJ Saunders - Neuropsychology, 2012 - psycnet.apa.org
Objective: Studies of Mild Cognitive Impairment (MCI) show elevated rates of conversion to
dementia at the group level. However, previous studies of the trajectory of MCI identify great …

High-intensity interval training improves cognitive flexibility in older adults

S Mekari, HF Neyedli, S Fraser, MW O'Brien, R Martins… - Brain sciences, 2020 - mdpi.com
Introduction: Regular aerobic exercise is associated with better executive function in older
adults. It is unclear if high-intensity-interval-training (HIIT) elicits moderate-intensity …

Effects of bilingualism on the age of onset and progression of MCI and AD: evidence from executive function tests.

E Bialystok, FIM Craik, MA Binns, L Ossher… - …, 2014 - psycnet.apa.org
Previous articles have reported that bilingualism is associated with a substantial delay in the
onset of both Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI). The present …