Clear cell renal cell carcinomas (ccRCCs) represent∼ 75% of RCC cases and account for
most RCC-associated deaths. Inter-and intratumoral heterogeneity (ITH) results in varying …

To elucidate the deregulated functional modules that drive clear cell renal cell carcinoma
(ccRCC), we performed comprehensive genomic, epigenomic, transcriptomic, proteomic …

Background There is increasing evidence that circular RNAs (circRNAs) have significant
regulatory roles in cancer development and progression; however, the expression patterns …

Background In 2014, 15 500 persons in Germany were given the diagnosis of renal cell
carcinoma. This disease is the third most common cancer of the urogenital system. The …

Tissue ablation techniques have emerged as a critical component of modern medical
practice and biomedical research, offering versatile solutions for treating various diseases …

Background Antibodies targeting programmed death-1 (PD-1) or programmed death-ligand
1 (PD-L1) have shown clinical activity in the treatment of metastatic renal cell carcinoma …

Background Renal cell carcinoma (RCC) is usually considered radioresistant, but
stereotactic radiation therapy (SRT) may increase local disease control. This study aimed to …

Background and purpose We previously demonstrated the safety of doses up to 48 Gy in 4
fractions with stereotactic body radiotherapy (SBRT) in poor surgical candidates with …

Background Renal cell carcinoma (RCC) is traditionally considered to be radioresistant.
Radiotherapy response rates are believed to improve with hypofractionated, high dose …

Clear cell renal cell carcinoma (ccRCC), a common form of RCC, is responsible for the high
mortality rate of kidney cancer. Dysregulations of glycoproteins have been shown to …