Breast cancer is a heterogeneous disease that affects one anatomic site, yet is
phenotypically variable. 1, 2 The identification of different biological subtypes occurs …

Breast cancer is a heterogeneous disease manifesting diversity at the molecular,
histological and clinical level. The development of breast cancer classification was centered …

Simple Summary HER2-low breast cancer is an emerging subtype for which very few data
are available, especially within the triple-negative breast cancer (TNBC) group. Our aim was …

Background Several expression array studies identified molecular apocrine breast cancer
(BC) as a subtype that expresses androgen receptor (AR) but not estrogen receptor α. We …

Purpose. To determine intrinsic breast cancer subtypes represented within categories
defined by quantitative hormone receptor (HR) and HER2 expression. Methods. We merged …

Context.—The pioneering works on molecular classification (MC) by Perou and Sorlie et al
in the early 2000s using global gene expression profiling identified 5 intrinsic subtypes of …

Triple-negative breast cancer (TNBC) is an aggressive disease with outcomes inferior to
those of other breast cancer subtypes. No targeted therapies are currently approved for …

Triple-negative breast cancer (TNBC) comprises a highly diverse collection of cancers.
Here, we review this diversity both in terms of gene expression subtypes and the repertoire …

Animal models of cancer have been instrumental in advancing our understanding of the
biology of tumor initiation and progression, in studying gene function and in performing …

Triple negative breast cancer (TNBC) is a complex and malignant breast cancer subtype that
lacks expression of the estrogen receptor (ER), progesterone receptor (PR) and human …