Osteoarthritis (OA) is a growing public health problem across the globe, affecting more than
half of the over 65 population. In the past, OA was considered a wear and tear disease …

Osteoarthritis (OA) affects 240 million people globally. Few studies have examined the links
between osteoarthritis and the Mediterranean diet (MD). The aim of this paper was to …

Objective To study the relative contribution of surrogates for mechanical stress and systemic
processes with osteoarthritis (OA) in weight-bearing and non-weight-bearing joints. Methods …

Projected increases in the prevalence of both diabetes mellitus (DM) and osteoarthritis (OA)
ensure their common co-existence. In an era of increasing attention to personalized …

Cartilage loss is irreversible, and to date, no effective pharmacotherapies are available to
protect or regenerate cartilage. Quantitative prestructural/compositional MR imaging …

Purpose To investigate the association of weight loss with progression of cartilage changes
at magnetic resonance (MR) imaging over 48 months in overweight and obese participants …

Osteoarthritis (OA) is the most common chronic joint disorder and its prevalence increases
rapidly during midlife. Complex interactions of genetic alterations, sex hormone deficit, and …

Objective To investigate compositional cartilage changes measured with 3T MRI-based T2
values over 48 months in overweight and obese individuals with different degrees of weight …

The Osteoarthritis Initiative (OAI) is a multicentre, prospective, observational, cohort study of
knee osteoarthritis (OA) that began recruitment in 2004. The OAI provides public access to …

Background Magnetic resonance imaging (MRI) T2 and T1ρ relaxation are increasingly
being proposed as imaging biomarkers potentially capable of detecting biochemical …