[HTML][HTML] The emerging role of RNA modifications in the regulation of mRNA stability
SH Boo, YK Kim - Experimental & molecular medicine, 2020 - nature.com
Many studies have highlighted the importance of the tight regulation of mRNA stability in the
control of gene expression. mRNA stability largely depends on the mRNA nucleotide …
control of gene expression. mRNA stability largely depends on the mRNA nucleotide …
Biomolecular condensates: organizers of cellular biochemistry
Biomolecular condensates are micron-scale compartments in eukaryotic cells that lack
surrounding membranes but function to concentrate proteins and nucleic acids. These …
surrounding membranes but function to concentrate proteins and nucleic acids. These …
P-bodies: composition, properties, and functions
Processing bodies (P-bodies) are cytoplasmic ribonucleoprotein (RNP) granules primarily
composed of translationally repressed mRNAs and proteins related to mRNA decay …
composed of translationally repressed mRNAs and proteins related to mRNA decay …
Principles and properties of stress granules
DSW Protter, R Parker - Trends in cell biology, 2016 - cell.com
Stress granules are assemblies of untranslating messenger ribonucleoproteins (mRNPs)
that form from mRNAs stalled in translation initiation. Stress granules form through …
that form from mRNAs stalled in translation initiation. Stress granules form through …
[HTML][HTML] Compositional control of phase-separated cellular bodies
Cellular bodies such as P bodies and PML nuclear bodies (PML NBs) appear to be phase-
separated liquids organized by multivalent interactions among proteins and RNA molecules …
separated liquids organized by multivalent interactions among proteins and RNA molecules …
Protein phase separation: a new phase in cell biology
Cellular compartments and organelles organize biological matter. Most well-known
organelles are separated by a membrane boundary from their surrounding milieu. There are …
organelles are separated by a membrane boundary from their surrounding milieu. There are …
[HTML][HTML] Emerging roles for intermolecular RNA-RNA interactions in RNP assemblies
B Van Treeck, R Parker - Cell, 2018 - cell.com
Eukaryotic cells contain large assemblies of RNA and protein, referred to as
ribonucleoprotein (RNP) granules, which include cytoplasmic P-bodies, stress granules, and …
ribonucleoprotein (RNP) granules, which include cytoplasmic P-bodies, stress granules, and …
[HTML][HTML] ATPase-modulated stress granules contain a diverse proteome and substructure
Stress granules are mRNA-protein granules that form when translation initiation is limited,
and they are related to pathological granules in various neurodegenerative diseases. Super …
and they are related to pathological granules in various neurodegenerative diseases. Super …
[HTML][HTML] Distinct stages in stress granule assembly and disassembly
Stress granules are non-membrane bound RNA-protein (RNP) assemblies that form when
translation initiation is limited and contain a biphasic structure with stable core structures …
translation initiation is limited and contain a biphasic structure with stable core structures …
[HTML][HTML] Formation and maturation of phase-separated liquid droplets by RNA-binding proteins
Eukaryotic cells possess numerous dynamic membrane-less organelles, RNP granules,
enriched in RNA and RNA-binding proteins containing disordered regions. We demonstrate …
enriched in RNA and RNA-binding proteins containing disordered regions. We demonstrate …