[HTML][HTML] The emerging role of RNA modifications in the regulation of mRNA stability

SH Boo, YK Kim - Experimental & molecular medicine, 2020 - nature.com
Many studies have highlighted the importance of the tight regulation of mRNA stability in the
control of gene expression. mRNA stability largely depends on the mRNA nucleotide …

Biomolecular condensates: organizers of cellular biochemistry

SF Banani, HO Lee, AA Hyman… - Nature reviews Molecular …, 2017 - nature.com
Biomolecular condensates are micron-scale compartments in eukaryotic cells that lack
surrounding membranes but function to concentrate proteins and nucleic acids. These …

P-bodies: composition, properties, and functions

Y Luo, Z Na, SA Slavoff - Biochemistry, 2018 - ACS Publications
Processing bodies (P-bodies) are cytoplasmic ribonucleoprotein (RNP) granules primarily
composed of translationally repressed mRNAs and proteins related to mRNA decay …

Principles and properties of stress granules

DSW Protter, R Parker - Trends in cell biology, 2016 - cell.com
Stress granules are assemblies of untranslating messenger ribonucleoproteins (mRNPs)
that form from mRNAs stalled in translation initiation. Stress granules form through …

[HTML][HTML] Compositional control of phase-separated cellular bodies

SF Banani, AM Rice, WB Peeples, Y Lin, S Jain… - Cell, 2016 - cell.com
Cellular bodies such as P bodies and PML nuclear bodies (PML NBs) appear to be phase-
separated liquids organized by multivalent interactions among proteins and RNA molecules …

Protein phase separation: a new phase in cell biology

S Boeynaems, S Alberti, NL Fawzi, T Mittag… - Trends in cell …, 2018 - cell.com
Cellular compartments and organelles organize biological matter. Most well-known
organelles are separated by a membrane boundary from their surrounding milieu. There are …

[HTML][HTML] Emerging roles for intermolecular RNA-RNA interactions in RNP assemblies

B Van Treeck, R Parker - Cell, 2018 - cell.com
Eukaryotic cells contain large assemblies of RNA and protein, referred to as
ribonucleoprotein (RNP) granules, which include cytoplasmic P-bodies, stress granules, and …

[HTML][HTML] ATPase-modulated stress granules contain a diverse proteome and substructure

S Jain, JR Wheeler, RW Walters, A Agrawal, A Barsic… - Cell, 2016 - cell.com
Stress granules are mRNA-protein granules that form when translation initiation is limited,
and they are related to pathological granules in various neurodegenerative diseases. Super …

[HTML][HTML] Distinct stages in stress granule assembly and disassembly

JR Wheeler, T Matheny, S Jain, R Abrisch, R Parker - elife, 2016 - elifesciences.org
Stress granules are non-membrane bound RNA-protein (RNP) assemblies that form when
translation initiation is limited and contain a biphasic structure with stable core structures …

[HTML][HTML] Formation and maturation of phase-separated liquid droplets by RNA-binding proteins

Y Lin, DSW Protter, MK Rosen, R Parker - Molecular cell, 2015 - cell.com
Eukaryotic cells possess numerous dynamic membrane-less organelles, RNP granules,
enriched in RNA and RNA-binding proteins containing disordered regions. We demonstrate …