Severe covid-19 pneumonia: pathogenesis and clinical management

AH Attaway, RG Scheraga, A Bhimraj, M Biehl… - bmj, 2021 - bmj.com
Severe covid-19 pneumonia has posed critical challenges for the research and medical
communities. Older age, male sex, and comorbidities increase the risk for severe disease …

[HTML][HTML] COVID-19-associated acute respiratory distress syndrome: is a different approach to management warranted?

E Fan, JR Beitler, L Brochard, CS Calfee… - The Lancet …, 2020 - thelancet.com
The COVID-19 pandemic has seen a surge of patients with acute respiratory distress
syndrome (ARDS) in intensive care units across the globe. As experience of managing …

Ventilation management and clinical outcomes in invasively ventilated patients with COVID-19 (PRoVENT-COVID): a national, multicentre, observational cohort study

M Botta, AM Tsonas, J Pillay, LS Boers… - The lancet Respiratory …, 2021 - thelancet.com
Background Little is known about the practice of ventilation management in patients with
COVID-19. We aimed to describe the practice of ventilation management and to establish …

Pulmonary angiopathy in severe COVID-19: physiologic, imaging, and hematologic observations

BV Patel, DJ Arachchillage, CA Ridge… - American journal of …, 2020 - atsjournals.org
Rationale: Clinical and epidemiologic data in coronavirus disease (COVID-19) have
accrued rapidly since the outbreak, but few address the underlying pathophysiology …

Pathophysiology of acute respiratory distress syndrome and COVID-19 lung injury

KE Swenson, ER Swenson - Critical care clinics, 2021 - criticalcare.theclinics.com
Acute respiratory distress syndrome (ARDS) is a complex syndrome of acute lung injury
leading to noncardiogenic pulmonary edema from many causes that is heterogenous in its …

Mechanical ventilation parameters in critically ill COVID-19 patients: a scoping review

G Grasselli, E Cattaneo, G Florio, M Ippolito, A Zanella… - Critical Care, 2021 - Springer
Background The mortality of critically ill patients with COVID-19 is high, particularly among
those receiving mechanical ventilation (MV). Despite the high number of patients treated …

Respiratory physiology of COVID-19-induced respiratory failure compared to ARDS of other etiologies

DL Grieco, F Bongiovanni, L Chen, LS Menga… - Critical Care, 2020 - Springer
Background Whether respiratory physiology of COVID-19-induced respiratory failure is
different from acute respiratory distress syndrome (ARDS) of other etiologies is unclear. We …

[HTML][HTML] From ARDS to pulmonary fibrosis: the next phase of the COVID-19 pandemic?

JE Michalski, JS Kurche, DA Schwartz - Translational Research, 2022 - Elsevier
While the coronavirus disease 19 (COVID-19) pandemic has transformed the medical and
scientific communites since it was first reported in late 2019, we are only beginning to …

Myocardial injury in severe COVID-19 compared with non–COVID-19 acute respiratory distress syndrome

TS Metkus, LJ Sokoll, AS Barth, MJ Czarny, AG Hays… - Circulation, 2021 - Am Heart Assoc
Background: Knowledge gaps remain in the epidemiology and clinical implications of
myocardial injury in coronavirus disease 2019 (COVID-19). We aimed to determine the …

COVID-19 versus non–COVID-19 acute respiratory distress syndrome: comparison of demographics, physiologic parameters, inflammatory biomarkers, and clinical …

W Bain, H Yang, FA Shah, T Suber… - Annals of the …, 2021 - atsjournals.org
Rationale: There is an urgent need for improved understanding of the mechanisms and
clinical characteristics of acute respiratory distress syndrome (ARDS) due to coronavirus …