DNA and chromosome damage induced by bleomycin in mammalian cells: An update

AD Bolzán, MS Bianchi - Mutation Research/Reviews in Mutation Research, 2018 - Elsevier
Bleomycin (BLM) is an antibiotic isolated from Streptomyces verticillus. It has radiomimetic
actions on DNA thus it has been widely used in clinical chemotherapy for the treatment of …

[HTML][HTML] Cosmic ionizing radiation: a DNA damaging agent that may underly excess cancer in flight crews

SM Toprani, C Scheibler, I Mordukhovich… - International Journal of …, 2024 - mdpi.com
In the United States, the Federal Aviation Administration has officially classified flight crews
(FC) consisting of commercial pilots, cabin crew, or flight attendants as “radiation workers” …

Ionizing radiation exposure and basal cell carcinoma pathogenesis

C Li, M Athar - Radiation research, 2016 - meridian.allenpress.com
This commentary summarizes studies showing risk of basal cell carcinoma (BCC)
development in relationship to environmental, occupational and therapeutic exposure to …

A functional polymorphism at microRNA-629-binding site in the 3′-untranslated region of NBS1 gene confers an increased risk of lung cancer in …

L Yang, Y Li, M Cheng, D Huang, J Zheng, B Liu… - …, 2012 - academic.oup.com
The genetic variations in NBS1 gene have been reported to be associated with cancer risk.
The polymorphisms in 3′-untranslated region (3′-UTR) of NBS1 might affect gene's …

[HTML][HTML] Numerical model for computation of effective and ambient dose equivalent at flight altitudes-Application for dose assessment during GLEs

A Mishev, I Usoskin - Journal of Space Weather and Space Climate, 2015 - swsc-journal.org
A numerical model for assessment of the effective dose and ambient dose equivalent
produced by secondary cosmic ray particles of galactic and solar origin at commercial …

A Sequence Polymorphism in miR-608 Predicts Recurrence after Radiotherapy for Nasopharyngeal Carcinoma

J Zheng, J Deng, M Xiao, L Yang, L Zhang, Y You… - Cancer research, 2013 - AACR
Nasopharyngeal carcinoma is treated with radiotherapy and other modalities, but there is
little information on individual genetic factors to help predict and improve patient outcomes …

[HTML][HTML] Interplay between air travel, genome integrity, and COVID-19 risk vis-a-vis flight crew

SM Toprani, C Scheibler, ZD Nagel - Frontiers in Public Health, 2020 - frontiersin.org
During air travel, flight crew (flight attendants, pilots) can be exposed to numerous flight-
related environmental DNA damaging agents that may be at the root of an excess risk of …

The functional polymorphism of NBS1 p. Glu185Gln is associated with an increased risk of lung cancer in Chinese populations: Case–control and a meta-analysis

W Fang, F Qiu, L Zhang, J Deng, H Zhang… - Mutation Research …, 2014 - Elsevier
NBS1 plays pivotal roles in maintaining genomic stability and cancer development. The
exon variant rs1805794G> C (p. Glu185Gln) of NBS1 has been frequently studied in several …

[HTML][HTML] Aircrew Health: A Systematic Review of Physical Agents as Occupational Risk Factors

AC Russo, EC Marqueze, MSG Furst… - International Journal of …, 2023 - mdpi.com
The primary objective of this systematic review was to analyze the main physical agents
representing risk factors for commercial aircrew, together with their consequences. The …

Bleomycin-induced Chromosomal Aberrations in Epstein-Barr Virus-Transformed Human Lymphoblastoid Cells

AG Cardozo, DC Castrogiovanni, AD Bolzán - Mutation Research-Genetic …, 2024 - Elsevier
We have evaluated the induction of complete (ie, without open ends) and incomplete (ie,
with non-rejoined or open ends) chromosomal aberrations by the radiomimetic antibiotic …