Cardiac fibrosis
NG Frangogiannis - Cardiovascular research, 2021 - academic.oup.com
Myocardial fibrosis, the expansion of the cardiac interstitium through deposition of
extracellular matrix proteins, is a common pathophysiologic companion of many different …
extracellular matrix proteins, is a common pathophysiologic companion of many different …
Cardiac fibrosis: Cell biological mechanisms, molecular pathways and therapeutic opportunities
NG Frangogiannis - Molecular aspects of medicine, 2019 - Elsevier
Cardiac fibrosis is a common pathophysiologic companion of most myocardial diseases,
and is associated with systolic and diastolic dysfunction, arrhythmogenesis, and adverse …
and is associated with systolic and diastolic dysfunction, arrhythmogenesis, and adverse …
[HTML][HTML] The role of α-smooth muscle actin in fibroblast-mediated matrix contraction and remodeling
Cardiac myofibroblasts play an important role in myocardial remodeling. Although α-smooth
muscle actin (α-SMA) expression is the hallmark of mature myofibroblasts, its role in …
muscle actin (α-SMA) expression is the hallmark of mature myofibroblasts, its role in …
Targeting cardiac fibrosis in heart failure with preserved ejection fraction: mirage or miracle?
Cardiac fibrosis is central to the pathology of heart failure, particularly heart failure with
preserved ejection fraction (HF p EF). Irrespective of the underlying profibrotic condition (eg …
preserved ejection fraction (HF p EF). Irrespective of the underlying profibrotic condition (eg …
[HTML][HTML] Modified citrus pectin ameliorates myocardial fibrosis and inflammation via suppressing galectin-3 and TLR4/MyD88/NF-κB signaling pathway
GR Xu, C Zhang, HX Yang, JH Sun, Y Zhang… - Biomedicine & …, 2020 - Elsevier
Myocardial fibrosis (MF) plays a key role in the development and progression of heart failure
(HF) with limited effective therapies. Galectin-3 (Gal-3) is a biomarker associated with …
(HF) with limited effective therapies. Galectin-3 (Gal-3) is a biomarker associated with …
Catecholamine-induced cardiotoxicity: a critical element in the pathophysiology of stroke-induced heart injury
Y Du, LJ Demillard, J Ren - Life Sciences, 2021 - Elsevier
Cerebrovascular diseases such as ischemic stroke, brain hemorrhage, and subarachnoid
hemorrhage provoke cardiac complications such as heart failure, neurogenic stress-related …
hemorrhage provoke cardiac complications such as heart failure, neurogenic stress-related …
Plasma and cardiac galectin-3 in patients with heart failure reflects both inflammation and fibrosis: implications for its use as a biomarker
C Besler, D Lang, D Urban, KP Rommel… - Circulation: heart …, 2017 - Am Heart Assoc
Background—Galectin (Gal)-3 is a β-galactoside-binding lectin and currently intensely
studied as a biomarker in heart failure. Gal-3 also exerts proinflammatory effects, at least in …
studied as a biomarker in heart failure. Gal-3 also exerts proinflammatory effects, at least in …
[HTML][HTML] The diagnostic and therapeutic potential of galectin-3 in cardiovascular diseases
G Sygitowicz, A Maciejak-Jastrzębska, D Sitkiewicz - Biomolecules, 2021 - mdpi.com
Galectin-3 plays a prominent role in chronic inflammation and has been implicated in the
development of many disease conditions, including heart disease. Galectin-3, a regulatory …
development of many disease conditions, including heart disease. Galectin-3, a regulatory …
[HTML][HTML] Colchicine alleviates inflammation and improves diastolic dysfunction in heart failure rats with preserved ejection fraction
S Shen, J Duan, J Hu, Y Qi, L Kang, K Wang… - European Journal of …, 2022 - Elsevier
Purpose Several studies have reported that colchicine attenuates cardiac inflammation and
improves cardiac function in myocardial infarction and atrial fibrillation. However, no study …
improves cardiac function in myocardial infarction and atrial fibrillation. However, no study …
[HTML][HTML] Biomarkers as predictors of recurrence of atrial fibrillation post ablation: an updated and expanded systematic review and meta-analysis
V Boyalla, L Harling, A Snell, I Kralj-Hans… - Clinical Research in …, 2022 - Springer
Background A high proportion of patients undergoing catheter ablation (CA) for atrial
fibrillation (AF) experience recurrence of arrhythmia. This meta-analysis aims to identify pre …
fibrillation (AF) experience recurrence of arrhythmia. This meta-analysis aims to identify pre …