Microbiome and human health: current understanding, engineering, and enabling technologies
The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …
Plasmids pick a bacterial partner before committing to conjugation
Bacterial conjugation was first described by Lederberg and Tatum in the 1940s following the
discovery of the F plasmid. During conjugation a plasmid is transferred unidirectionally from …
discovery of the F plasmid. During conjugation a plasmid is transferred unidirectionally from …
The F-pilus biomechanical adaptability accelerates conjugative dissemination of antimicrobial resistance and biofilm formation
Conjugation is used by bacteria to propagate antimicrobial resistance (AMR) in the
environment. Central to this process are widespread conjugative F-pili that establish the …
environment. Central to this process are widespread conjugative F-pili that establish the …
Link between antibiotic persistence and antibiotic resistance in bacterial pathogens
W Eisenreich, T Rudel, J Heesemann… - Frontiers in cellular and …, 2022 - frontiersin.org
Both, antibiotic persistence and antibiotic resistance characterize phenotypes of survival in
which a bacterial cell becomes insensitive to one (or even) more antibiotic (s). However, the …
which a bacterial cell becomes insensitive to one (or even) more antibiotic (s). However, the …
Unlocking the potential of microbiome editing: a review of conjugation‐based delivery
P Dorado‐Morales, M Lambérioux… - Molecular …, 2024 - Wiley Online Library
In recent decades, there has been a rapid increase in the prevalence of multidrug‐resistant
pathogens, posing a challenge to modern antibiotic‐based medicine. This has highlighted …
pathogens, posing a challenge to modern antibiotic‐based medicine. This has highlighted …
Prevalence of antibiotic resistance genes and virulence factors in the sediment of WWTP effluent-dominated rivers
Y Zou, Z Xiao, L Wang, Y Wang, H Yin, Y Li - Science of the Total …, 2023 - Elsevier
In the context of increasing aridity due to climate changes, effluent from wastewater
treatment plants (WWTPs) became dominant in some rivers. However, the prevalence of …
treatment plants (WWTPs) became dominant in some rivers. However, the prevalence of …
Non-antibiotic compounds associated with humans and the environment can promote horizontal transfer of antimicrobial resistance genes
I Alav, MMC Buckner - Critical Reviews in Microbiology, 2024 - Taylor & Francis
Horizontal gene transfer plays a key role in the global dissemination of antimicrobial
resistance (AMR). AMR genes are often carried on self-transmissible plasmids, which are …
resistance (AMR). AMR genes are often carried on self-transmissible plasmids, which are …
Forecasting antimicrobial resistance evolution
Antimicrobial resistance (AMR) is a major global health issue. Current measures for tackling
it comprise mainly the prudent use of drugs, the development of new drugs, and rapid …
it comprise mainly the prudent use of drugs, the development of new drugs, and rapid …
In situ, in vivo, and in vitro approaches for studying AMR plasmid conjugation in the gut microbiome
C Kessler, J Hou, O Neo… - FEMS Microbiology …, 2023 - academic.oup.com
Antimicrobial resistance (AMR) is a global threat, with evolution and spread of resistance to
frontline antibiotics outpacing the development of novel treatments. The spread of AMR is …
frontline antibiotics outpacing the development of novel treatments. The spread of AMR is …
Prevalence and Population Diversity of Listeria monocytogenes Isolated from Dairy Cattle Farms in the Cantabria Region of Spain
Simple Summary The origin and prevalence of Listeria monocytogenes was studied in dairy
cattle farms in order to examine its diversity and determine its possible persistence in …
cattle farms in order to examine its diversity and determine its possible persistence in …