Oxidative stress is the result of the imbalance between reactive oxygen species (ROS)
formation and enzymatic and nonenzymatic antioxidants. Biomarkers of oxidative stress are …

NRF2 has been traditionally considered as a tumor suppressor because its cytoprotective
functions are deemed to be the main cellular defense mechanism against exogenous and …

Acute lung injury (ALI) carries a mortality rate of~ 50% and is a hot topic in the world of
critical illness research. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a critical …

Cancer cells are hallmarked by high proliferation and imbalanced redox consumption and
signaling. Various oncogenic pathways such as proliferation and evading cell death …

Acute lung injury (ALI) has gained increased attention in the field of critical illness research
and is associated with a fatality rate of approximately 50%. Nuclear factor erythroid 2‐related …

The cytosolic selenoprotein thioredoxin reductase 1 (TrxR1, TXNRD1), and to some extent
mitochondrial TrxR2 (TXNRD2), can be inhibited by a wide range of electrophilic …

Abstract Hydrogen peroxide (H 2 O 2) is involved in various signal transduction pathways
and cell fate decisions. The mechanism of the so called “redox signaling” includes the H 2 O …

Inflammatory responses play pivotal roles in cancer development, including tumor initiation,
promotion, progression, and metastasis. Cytokines are now recognized as important …

Emerging research has revealed regulation of colorectal cancer metabolism by bacteria.
Fusobacterium nucleatum (Fn) plays a crucial role in the development of colorectal cancer …

With age, skeletal muscle stem cells (MuSCs) activate out of quiescence more slowly and
with increased death, leading to defective muscle repair. To explore the molecular …