The cyclic polyol myo-inositol is a key molecule in many different metabolic pathways
among all organisms; in addition, it is fundamental for osmotic balance in the mammalian …

More than 1.5 million fungal species are estimated to live in vastly different environmental
niches. Despite each unique host environment, fungal cells sense certain fundamentally …

ABSTRACT pH homeostasis is critical for all organisms; in the fungal pathogen Candida
albicans, pH adaptation is critical for virulence in distinct host niches. We demonstrate that …

The evolution of drug resistance has a profound impact on human health. Candida glabrata
is a leading human fungal pathogen that can rapidly evolve resistance to echinocandins …

Candida albicans, a major opportunistic fungal pathogen, is frequently found together with
Streptococcus mutans in dental biofilms associated with severe childhood caries (tooth …

Although considered rare, the emergent Candida haemulonii species complex, formed by C.
haemulonii sensu stricto (Ch), C. duobushaemulonii (Cd) and C. haemulonii var. vulnera …

Phospholipid biosynthetic pathways play crucial roles in the virulence of several pathogens;
however, little is known about how phospholipid synthesis affects pathogenesis in fungi …

Candida dubliniensis is an emerging pathogenic yeast species closely related to Candida
albicans and frequently found colonizing or infecting the oral cavities of HIV/AIDS patients …

Cryptococcus neoformans is the most common cause of fungal meningitis, with high
mortality and morbidity. The reason for the frequent occurrence of Cryptococcus infection in …

myo-Inositol (inositol) is an essential nutrient that is used for building phosphatidylinositol
and its derivatives in eukaryotes and even in some eubacteria such as the mycobacteria. As …