“Stress” is 80 years old: From Hans Selye original paper in 1936 to recent advances in GI ulceration

S Szabo, M Yoshida, J Filakovszky… - Current pharmaceutical …, 2017 - ingentaconnect.com
The first scientific publication on 'general adaption syndrome', or as we know today 'biologic
stress' has been published in Nature in 1936 by the 29-year old Hans Selye. His results in …

BPC157 as potential agent rescuing from cancer cachexia

EA Kang, YM Han, JM An, YJ Park… - Current …, 2018 - ingentaconnect.com
Cancer cachexia, one of the metabolic syndromes caused by cancer, is a devastating and
miserable condition encountered in more than 50% of terminal cancer patients presenting …

Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation

MJ Hsieh, HT Liu, CN Wang, HY Huang, Y Lin… - Journal of Molecular …, 2017 - Springer
BPC 157, a pentadecapeptide with extensive healing effects, has recently been suggested
to contribute to angiogenesis. However, the underlying mechanism is not yet clear. The …

The effect of pentadecapeptide BPC 157 on hippocampal ischemia/reperfusion injuries in rats

J Vukojević, B Vrdoljak, D Malekinušić… - Brain and …, 2020 - Wiley Online Library
Background and purpose We focused on the, yet undescribed, therapy effect of the stable
gastric pentadecapeptide BPC 157 in hippocampal ischemia/reperfusion injuries, after …

Rat inferior caval vein (ICV) ligature and particular new insights with the stable gastric pentadecapeptide BPC 157

J Vukojević, M Siroglavić, K Kašnik, T Kralj… - Vascular …, 2018 - Elsevier
Rat inferior caval vein (ICV) ligation (up to the right ovarian vein (ROV)) commonly
represents a recapitulation of Virchow: with ligation leading to vessel injury, stasis …

[HTML][HTML] Pentadecapeptide BPC 157 resolves Pringle maneuver in rats, both ischemia and reperfusion

M Kolovrat, S Gojkovic, I Krezic… - World journal of …, 2020 - ncbi.nlm.nih.gov
BACKGROUND The Pringle maneuver [portal triad obstruction (PTO)] provides huge
disturbances during ischemia and even more thereafter in reperfusion. Contrarily, a possible …

[HTML][HTML] Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights

A Duzel, J Vlainic, M Antunovic… - World Journal of …, 2017 - ncbi.nlm.nih.gov
AIM To provide new insights in treatment of colitis and ischemia and reperfusion in rats
using stable gastric pentadecapeptide BPC 157. METHODS Medication [BPC 157, L-NAME …

Novel cytoprotective mediator, stable gastric pentadecapeptide BPC 157. Vascular recruitment and gastrointestinal tract healing

P Sikiric, R Rucman, B Turkovic… - Current …, 2018 - ingentaconnect.com
Years ago, we revealed a novel cytoprotective mediator, stable gastric pentadecapeptide
BPC 157, particular anti-ulcer peptide that heals different organs lesions when given as a …

[HTML][HTML] Stable gastric pentadecapeptide BPC 157, Robert's stomach cytoprotection/adaptive cytoprotection/organoprotection, and Selye's stress coping response …

P Sikiric, KB Hahm, AB Blagaic, A Tvrdeic… - Gut and liver, 2020 - ncbi.nlm.nih.gov
We reviewed again the significance of the stable gastric pentadecapeptide BPC 157 as a
likely mediator of Robert's stomach cytoprotection/adaptive cytoprotection and …

Occlusion of the Superior Mesenteric Artery in Rats Reversed by Collateral Pathways Activation: Gastric Pentadecapeptide BPC 157 Therapy Counteracts Multiple …

M Knezevic, S Gojkovic, I Krezic, H Zizek… - Biomedicines, 2021 - mdpi.com
Gastric pentadecapeptide BPC 157 therapy counteracts multiple organ dysfunction
syndrome in rats, which have permanent occlusion of the superior mesenteric artery close to …