Gut microbiome, metabolome, host immunity associated with inflammatory bowel disease and intervention of fecal microbiota transplantation
Gut dysbiosis has been associated with inflammatory bowel disease (IBD), one of the most
common gastrointestinal diseases. The microbial communities play essential roles in host …
common gastrointestinal diseases. The microbial communities play essential roles in host …
FODMAPs, inflammatory bowel disease and gut microbiota: updated overview on the current evidence
CD Simões, M Maganinho, AS Sousa - European journal of nutrition, 2022 - Springer
Purpose Based on the fermentable oligosaccharides, disaccharides, monosaccharides and
polyols (FODMAP) hypothesis, the low-FODMAP diet has been suggested as a potential …
polyols (FODMAP) hypothesis, the low-FODMAP diet has been suggested as a potential …
Probiotics (Lactobacillus plantarum HNU082) supplementation relieves ulcerative colitis by affecting intestinal barrier functions, immunity-related gene expression, gut …
Probiotics can effectively improve ulcerative colitis (UC), but the mechanism is still unclear.
Here, shotgun metagenome and transcriptome analyses were performed to explore the …
Here, shotgun metagenome and transcriptome analyses were performed to explore the …
Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont
P Kuffa, JM Pickard, A Campbell, M Yamashita… - Cell Host & Microbe, 2023 - cell.com
Exclusive enteral nutrition (EEN) with fiber-free diets is an effective steroid-sparing treatment
to induce clinical remission in children with Crohn's disease (CD). However, the mechanism …
to induce clinical remission in children with Crohn's disease (CD). However, the mechanism …
Discovery of disease-adapted bacterial lineages in inflammatory bowel diseases
A Kumbhari, TNH Cheng, AN Ananthakrishnan… - Cell Host & Microbe, 2024 - cell.com
Gut bacteria are implicated in inflammatory bowel disease (IBD), but the strains driving these
associations are unknown. Large-scale studies of microbiome evolution could reveal the …
associations are unknown. Large-scale studies of microbiome evolution could reveal the …
Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations
The microbiota in individual habitats differ in both relative composition and absolute
abundance. While sequencing approaches determine the relative abundances of taxa and …
abundance. While sequencing approaches determine the relative abundances of taxa and …
Antimicrobial overproduction sustains intestinal inflammation by inhibiting Enterococcus colonization
Loss of antimicrobial proteins such as REG3 family members compromises the integrity of
the intestinal barrier. Here, we demonstrate that overproduction of REG3 proteins can also …
the intestinal barrier. Here, we demonstrate that overproduction of REG3 proteins can also …
Genistein ameliorates inflammation and insulin resistance through mediation of gut microbiota composition in type 2 diabetic mice
R Yang, Q Jia, S Mehmood, S Ma, X Liu - European Journal of Nutrition, 2021 - Springer
Purpose Genistein (GEN) has been reported to have diverse biological activities, including
antioxidant, hypolipidemic, and antidiabetic effects. This study investigated whether the …
antioxidant, hypolipidemic, and antidiabetic effects. This study investigated whether the …
Linking human milk oligosaccharide metabolism and early life gut microbiota: Bifidobacteria and beyond
C Lordan, AK Roche, D Delsing, A Nauta… - Microbiology and …, 2024 - Am Soc Microbiol
Human milk oligosaccharides (HMOs) are complex, multi-functional glycans present in
human breast milk. They represent an intricate mix of heterogeneous structures which reach …
human breast milk. They represent an intricate mix of heterogeneous structures which reach …
Interplay of human gut microbiome in health and wellness
The gut microbiome analysis, with specific interest on their direct impact towards the human
health, is currently revolutionizing the unexplored frontiers of the pathogenesis and …
health, is currently revolutionizing the unexplored frontiers of the pathogenesis and …