Biocatalytic gateway to convert glycerol into 3-hydroxypropionic acid in waste-based biorefineries: Fundamentals, limitations, and potential research strategies

HM Zabed, S Akter, PF Rupani, J Akor, Y Zhang… - Biotechnology …, 2023 - Elsevier
Microbial conversion of bioenergy-derived waste glycerol into value-added chemicals has
emerged as an important bioprocessing technology due to its eco-friendliness, feasible …

Recent advances, challenges and metabolic engineering strategies in the biosynthesis of 3‐hydroxypropionic acid

B Liang, G Sun, X Zhang, Q Nie… - Biotechnology and …, 2022 - Wiley Online Library
As an attractive and valuable platform chemical, 3‐hydroxypropionic acid (3‐HP) can be
used to produce a variety of industrially important commodity chemicals and biodegradable …

Integration of enzymatic data in Bacillus subtilis genome-scale metabolic model improves phenotype predictions and enables in silico design of poly-γ-glutamic acid …

I Massaiu, L Pasotti, N Sonnenschein, E Rama… - Microbial cell …, 2019 - Springer
Background Genome-scale metabolic models (GEMs) allow predicting metabolic
phenotypes from limited data on uptake and secretion fluxes by defining the space of all the …

Production of 3-hydroxypropionic acid from renewable substrates by metabolically engineered microorganisms: a review

X Wang, Z Cui, X Sun, Z Wang, T Chen - Molecules, 2023 - mdpi.com
3-Hydroxypropionic acid (3-HP) is a platform chemical with a wide range of existing and
potential applications, including the production of poly (3-hydroxypropionate)(P-3HP), a …

Process engineering for microbial production of 3-hydroxypropionic acid

F de Fouchécour, AK Sánchez-Castañeda… - Biotechnology …, 2018 - Elsevier
Due to concerns about the unsustainability and predictable shortage of fossil feedstocks,
research efforts are currently being made to develop new processes for production of …

Biological production of 3-hydroxypropionic acid: an update on the current status

L Matsakas, K Hrůzová, U Rova, P Christakopoulos - Fermentation, 2018 - mdpi.com
The production of high added-value chemicals from renewable resources is a necessity in
our attempts to switch to a more sustainable society. 3-Hydroxypropionic acid (3HP) is a …

[HTML][HTML] Biosynthesis pathways and strategies for improving 3-hydroxypropionic acid production in bacteria

P Zhao, P Tian - World Journal of Microbiology and Biotechnology, 2021 - Springer
Hydroxypropionic acid (3-HP) represents an economically important platform compound
from which a panel of bulk chemicals can be derived. Compared with petroleum-dependent …

ecBSU1: A Genome-Scale Enzyme-Constrained Model of Bacillus subtilis Based on the ECMpy Workflow

K Wu, Z Mao, Y Mao, J Niu, J Cai, Q Yuan, L Yun… - Microorganisms, 2023 - mdpi.com
Genome-scale metabolic models (GEMs) play an important role in the phenotype prediction
of microorganisms, and their accuracy can be further improved by integrating other types of …

Production of 3-hydroxypropanoic acid from glycerol by metabolically engineered bacteria

C Jers, A Kalantari, A Garg, I Mijakovic - Frontiers in Bioengineering …, 2019 - frontiersin.org
3-hydroxypropanoic acid (3-HP) is a valuable platform chemical with a high demand in the
global market. 3-HP can be produced from various renewable resources. It is used as a …

High‐level production of 3‐hydroxypropionic acid from glycerol as a sole carbon source using metabolically engineered Escherichia coli

JW Kim, YS Ko, TU Chae, SY Lee - Biotechnology and …, 2020 - Wiley Online Library
As climate change is an important environmental issue, the conventional petrochemical‐
based processes to produce valuable chemicals are being shifted toward eco‐friendly …