Smoking, alcohol consumption and disease-specific outcomes in rheumatic and musculoskeletal diseases (RMDs): systematic reviews informing the 2021 EULAR …

M Wieczorek, JM Gwinnutt, M Ransay-Colle… - RMD open, 2022 - rmdopen.bmj.com
Background A EULAR taskforce was convened to develop recommendations for lifestyle
behaviours in rheumatic and musculoskeletal diseases (RMDs). The aim of this paper was …

Mechanisms, impact and management of pain in rheumatoid arthritis

DA Walsh, DF McWilliams - Nature Reviews Rheumatology, 2014 - nature.com
People with rheumatoid arthritis (RA) identify pain as their most important symptom, one that
often persists despite optimal control of inflammatory disease. RA pain arises from multiple …

Autoantibodies to citrullinated proteins may induce joint pain independent of inflammation

G Wigerblad, DB Bas, C Fernades-Cerqueira… - Annals of the …, 2016 - ard.bmj.com
Objective An interesting and so far unexplained feature of chronic pain in autoimmune
disease is the frequent disconnect between pain and inflammation. This is illustrated well in …

Mechanisms for joint pain in rheumatoid arthritis (RA): from cytokines to central sensitization

A Zhang, YC Lee - Current osteoporosis reports, 2018 - Springer
Abstract Purpose of Review Pain in rheumatoid arthritis (RA) may be due to different
etiologies, ranging from peripheral inflammation to dysregulation of central nervous system …

[PDF][PDF] Pain mechanisms in rheumatoid arthritis

DF McWilliams, DA Walsh - Clin exp rheumatol, 2017 - clinexprheumatol.org
Understanding of the causes and underlying mechanisms of pain in people with RA is
rapidly changing. With the advent of more effective disease modifying drugs, joint …

Non-inflammatory causes of pain in patients with rheumatoid arthritis

SD Boyden, IN Hossain, A Wohlfahrt… - Current rheumatology …, 2016 - Springer
Although pain in rheumatoid arthritis (RA) is frequently thought to be inflammatory in nature,
the association between measures of inflammation and pain intensity is low. This …

Pain and affective distress in arthritis: relationship to immunity and inflammation

M Harth, WR Nielson - Expert review of clinical immunology, 2019 - Taylor & Francis
Introduction: Most arthritides are associated with pain and psychological distress (clinically
significant depression and anxiety). Pain and depression are mutually exacerbating; both …

The outcome and cost-effectiveness of nurse-led care in people with rheumatoid arthritis: a multicentre randomised controlled trial

M Ndosi, M Lewis, C Hale, H Quinn, S Ryan… - Annals of the …, 2014 - ard.bmj.com
Objective To determine the clinical effectiveness and cost-effectiveness of nurse-led care
(NLC) for people with rheumatoid arthritis (RA). Methods In a multicentre pragmatic …

A cross-sectional study of pain sensitivity, disease-activity assessment, mental health, and fibromyalgia status in rheumatoid arthritis

N Joharatnam, DF McWilliams, D Wilson… - Arthritis research & …, 2015 - Springer
Introduction Pain remains the most important problem for people with rheumatoid arthritis
(RA). Active inflammatory disease contributes to pain, but pain due to non-inflammatory …

[PDF][PDF] Remaining pain in early rheumatoid arthritis patients treated with methotrexate

R Altawil, S Saevarsdottir, S Wedrén… - Arthritis care & …, 2016 - Wiley Online Library
Objective To investigate the frequency of remaining pain in early rheumatoid arthritis (RA)
after 3 months of treatment with methotrexate as the only disease modifying antirheumatic …