Mesenchymal stem cells for neurological disorders

A Andrzejewska, S Dabrowska, B Lukomska… - Advanced …, 2021 - Wiley Online Library
Neurological disorders are becoming a growing burden as society ages, and there is a
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …

Recent advances in traumatic brain injury

A Khellaf, DZ Khan, A Helmy - Journal of neurology, 2019 - Springer
Traumatic brain injury (TBI) is the most common cause of death and disability in those aged
under 40 years in the UK. Higher rates of morbidity and mortality are seen in low-income …

Sex differences in traumatic brain injury: what we know and what we should know

RP Gupte, WM Brooks, RR Vukas, JD Pierce… - Journal of …, 2019 - liebertpub.com
There is growing recognition of the problem of male bias in neuroscience research,
including in the field of traumatic brain injury (TBI) where fewer women than men are …

The far-reaching scope of neuroinflammation after traumatic brain injury

DW Simon, MJ McGeachy, H Bayır, RSB Clark… - Nature Reviews …, 2017 - nature.com
The'silent epidemic'of traumatic brain injury (TBI) has been placed in the spotlight as a result
of clinical investigations and popular press coverage of athletes and veterans with single or …

Increased miR‐124‐3p in microglial exosomes following traumatic brain injury inhibits neuronal inflammation and contributes to neurite outgrowth via their transfer …

S Huang, X Ge, J Yu, Z Han, Z Yin, Y Li… - The FASEB …, 2018 - Wiley Online Library
Neuronal inflammation is the characteristic pathologic change of acute neurologic
impairment and chronic traumatic encephalopathy after traumatic brain injury (TBI) …

Severe traumatic brain injury: targeted management in the intensive care unit

N Stocchetti, M Carbonara, G Citerio, A Ercole… - The Lancet …, 2017 - thelancet.com
Severe traumatic brain injury (TBI) is currently managed in the intensive care unit with a
combined medical–surgical approach. Treatment aims to prevent additional brain damage …

Acute management of traumatic brain injury

MA Vella, ML Crandall, MB Patel - Surgical Clinics, 2017 - surgical.theclinics.com
Trauma is the leading cause of death in individuals aged 1 to 45 years, with traumatic brain
injury (TBI) responsible for most these deaths; more than 50,000 deaths per year in the …

Chronic impact of traumatic brain injury on outcome and quality of life: a narrative review

N Stocchetti, ER Zanier - Critical Care, 2016 - Springer
Traditionally seen as a sudden, brutal event with short-term impairment, traumatic brain
injury (TBI) may cause persistent, sometimes life-long, consequences. While mortality after …

Revisiting traumatic brain injury: from molecular mechanisms to therapeutic interventions

A Jarrahi, M Braun, M Ahluwalia, RV Gupta, M Wilson… - Biomedicines, 2020 - mdpi.com
Studying the complex molecular mechanisms involved in traumatic brain injury (TBI) is
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …

Vaginal progesterone prophylaxis for preterm birth (the OPPTIMUM study): a multicentre, randomised, double-blind trial

JE Norman, N Marlow, CM Messow, A Shennan… - The lancet, 2016 - thelancet.com
Background Progesterone administration has been shown to reduce the risk of preterm birth
and neonatal morbidity in women at high risk, but there is uncertainty about longer term …